Trace Analysis Scientist - LC-MS & Drug Substances

Eurofins; Macclesfield; On-site; GBP 45,000 - 65,000; Full time

Benefits offered by this job

Health plan

Life assurance

Company pension

Perkbox access

Volunteer days

On-site parking

Job summary

Eurofins is recruiting an Analytical Scientist for trace analysis development at a world-class pharmaceutical facility in Macclesfield. You will develop, optimise and validate LC-MS-based methods to detect trace impurities in drug substances, supporting mutagenic impurity assessments and complex analytics.

The role requires hands-on LC-MS/MS/HRMS work, strong GMP knowledge, and excellent documentation skills in a collaborative environment with cross-functional teams.

Qualifications

• Degree in Chemistry, Analytical Chemistry or related scientific discipline with strong foundation in organic chemistry and analytical science.
• Pharmaceutical analytical experience in a development laboratory, with knowledge of drug development processes and the analysis of raw materials, intermediates and drug substances.
• Hands-on experience developing and applying advanced analytical techniques including LC-MS/MS, GC-MS/MS, GC-HRMS and LC-HRMS; NMR, IC or ICP-MS considered advantageous.
• Strong troubleshooting and problem-solving skills; ability to investigate analytical/instrumentation issues and develop solutions.
• Good understanding of GMP requirements and experience with electronic systems and MS Office; strong documentation and data management skills.
• Excellent communication and relationship-building skills; able to work independently and with teams to drive quality and continuous improvement.

Responsibilities

• Develop, optimise and validate advanced trace analysis methods using LC-MS and Orbitrap technologies to detect and quantify trace-level small molecules in raw materials, intermediates and drug substances.
• Provide technical expertise to project teams; support assessment of mutagenic impurities, nitrosamines and other trace analytes at parts-per-billion levels.
• Perform complex analytical investigations, interpret data and apply problem-solving to deliver accurate, high-quality results for clients.
• Support and enhance trace analysis capabilities by sharing specialist knowledge, advising stakeholders and delivering analytical programmes.
• Author and review analytical documentation, including testing plans, method development reports and validation protocols.
• Collaborate with multidisciplinary internal and external teams, communicating scientific concepts clearly while contributing to continuous improvement.

Skills

Analytical chemistry

Problem solving

Documentation

Communication

Education

Bachelor's/Master's in Chemistry

Tools

LC-MS/MS

GC-MS/MS

GC-HRMS

LC-HRMS

NMR

IC

ICP-MS

Job description

Eurofins is recruiting an Analytical Scientist for trace analysis development at a world-class pharmaceutical facility in Macclesfield. You will develop, optimise and validate LC-MS-based methods to detect trace impurities in drug substances, supporting mutagenic impurity assessments and complex analytics.

The role requires hands-on LC-MS/MS/HRMS work, strong GMP knowledge, and excellent documentation skills in a collaborative environment with cross-functional teams.