Senior Technical Specialist - DMPK

IQVIA LLC; Cambridge; On-site; GBP 65,000 - 85,000; Full time

Benefits offered by this job

Generous pension

Health cover

Bonus

Job summary

IQVIA in Cambridge seeks a Senior Technical Specialist - DMPK to lead bioanalytical work and mentor a lab team. You will develop and optimise LC-MS bioanalysis for DMPK studies, troubleshoot MS instrumentation and drive innovative assays within drug discovery projects.

The role combines hands-on laboratory work with project leadership, cross-functional collaboration and continuous improvement across multiple matrices and study designs. Strong communication and independence are essential.

Qualifications

• BSc or equivalent in relevant scientific area.
• Industry experience in pharma/biotech or commercial organisations.
• Expert user of Mass Spectrometry instrumentation.
• Bioanalytical method development for challenging analytes in complex matrices.
• Accurate planning, execution and troubleshooting.
• Good communication skills (verbal/written).
• Excellent team player with positive attitude.
• Creative problem solving.
• Ability to plan & execute work independently.
• Project management.
• Experience guiding/mentoring junior colleagues.
• LC-MS/MS maintenance and troubleshooting.
• Bespoke method development for small molecules.

Responsibilities

• Developing, optimising and executing bioanalysis of samples from in vivo DMPK studies for small and large molecule drug discovery projects.
• Extensive knowledge of modern UPLC-MS systems and software including chromatographic method development.
• Troubleshooting, maintenance, and optimisation of mass spectrometry and LC equipment.
• Analyse samples such as plasma, brain, urine, etc.
• Pharmacokinetic parameter determination and underlying principles.
• Lead scientific and technical projects, delivering high-quality data on time.
• Mentor and develop colleagues within a matrix environment.
• Drive innovation through novel assays and protocols.

Skills

LC-MS maintenance

Troubleshooting

Method development

Bioanalysis

Project leadership

Mentoring

Communication

Team player

Time management

Innovation

Education

BSc or equivalent

Tools

Mass Spectrometry instrumentation

LC-MS/MS

Job description

Are you already an experienced bioanalyst looking for your next role? Do you have refined skills in LC-MS maintenance and troubleshooting? Are you proficient in bespoke method development within small molecules? If you answered yes to any, or all of those questions then good news, our Cambridge site have a vacancy for a Senior Technical Specilaist - DMPK! A highly experienced lab and office based bioanalyst providing wide in-depth scientific and technical expertise to both multidisciplinary integrated Drug Discovery projects and standalone DMPK projects. This role combines hands-on bioanalytical expertise with project leadership, mentoring, and continuous improvement responsibilities to support small and large molecule drug discovery programmes. Offering you opportunities across varied DMPK and broader scientific projects and development across multiple scientiic and technical areas.

Main Tasks

• Developing, optimising and executing the bioanalysis of samples from in vivo DMPK studies for small and large molecule drug discovery projects in an early discovery setting.
• Extensive knowledge of modern UPLC-MS systems and software including chromatographic method development.
• Demonstrated ability to perform routine and complex troubleshooting, maintenance, and optimisation of mass spectrometry and LC equipment, ensuring reliable operation and rapid resolution of technical issues.
• Experience in the analysis of different sample types such as plasma, blood, brain, lung, bile, faeces, urine.
• Demonstrated experience of pharmacokinetic parameter determination and an understanding of the underlying principles.
• Comprehensive troubleshooting and problem-solving skills using both technical and scientific expertise.
• Strong organisation and time management skills alongside an inbuilt flexibility to adapt to change.
• Excellent communication skills and be an effective team player; these will be essential to successful execution of projects whilst working in a matrix and multi-skilled environment.
• Lead scientific and technical projects, ensuring delivery of high-quality data to agreed timelines.
• Drive innovation through the development of novel assays, protocols and analytical approaches.
• Mentor, coach and develop colleagues, acting as a technical role model and recognised subject matter expert.

Qualifications and Experience

• BSc or equivalent in relevant scientific area.
• Industry experience in pharma, biotech or other commercial organisations.
• Expert user of Mass Spectrometry instrumentation.
• Experience in the bioanalytical method development of challenging analytes, in complex matrices.
• Accurate & diligent experimental planning, execution and troubleshooting.
• Good communication skills (verbal/written) internally and externally.
• Excellent team player.
• Positive ‘can do’ attitude.
• Creative problem solving.
• Ability to plan & execute work independently.
• Project management.
• Strong organisation and time management skills alongside an inbuilt flexibility to adapt to change.
• Experience of guiding/mentoring junior colleagues.
• LC-MS/MS maintenance and troubleshooting.
• Bespoke method development for small molecules.

What We Offer You

• We offer a comprehensive benefits package from day one including generous pension, bonus and health cover.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide.

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create connections that accelerate the development and commercialization of innovative medical treatments.

Everything we do is part of a journey to improve patient outcomes and population health worldwide.

To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact.

No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere.

Thank you for your interest in growing your career with us.