Senior Spatial Transcriptomics Scientist

The Francis Crick Institute Limited; Greater London; Hybrid; GBP 45,000 - 65,000; Full time

Benefits offered by this job

Visas Sponsorship

Generous Leave & Pension

GP & Occupational health

Eye care & wellbeing programs

On-site restaurant & discounts

Job summary

The Francis Crick Institute is recruiting for a LABORATORY RESEARCH SCIENTIST/SENIOR laboratory position focused on supporting the lab's spatial transcriptomics pipeline using a custom in situ sequencing platform. The role links in vivo function, gene expression and neural connectivity, with training provided in-house and opportunities to advance scientific impact.

We welcome applicants at different career stages; appointment at LRS or SLRS level depending on experience.

Qualifications

• A degree or equivalent experience in Molecular Biology, Neuroscience, Bioengineering, or related field.
• Hands-on experience with RNA/DNA handling and tissue processing.
• Experience with in situ sequencing, spatial transcriptomics, or single-cell RNA-seq pipelines desirable.

Responsibilities

• Prepare tissue for in situ sequencing.
• Develop and optimise in situ sequencing protocols.
• Maintain inventories of sequencing reagents.
• Develop custom gene panels for profiling cell identity and state in situ.
• Quality control and preliminary analysis of in situ sequencing data.
• Maintain and develop sequencing setup.
• Train other users in lab techniques.
• Collaborate across projects and document experiments clearly.

Skills

Collaborative skills

Communication

Python/R/MATLAB

Independent optimization

Data analysis

Education

BSc or MSc in Molecular Biology/Neuroscience/Bioengineering

PhD in related field (SLRS)

Tools

Epifluorescence microscope

Confocal microscope

In situ sequencing platforms

Job description

The Francis Crick Institute is recruiting for a LABORATORY RESEARCH SCIENTIST/SENIOR laboratory position focused on supporting the lab's spatial transcriptomics pipeline using a custom in situ sequencing platform. The role links in vivo function, gene expression and neural connectivity, with training provided in-house and opportunities to advance scientific impact.

We welcome applicants at different career stages; appointment at LRS or SLRS level depending on experience.