Senior Scientist, Automated Diagnostic Systems

BioTalent; Oxford; Sur place; GBP 70 000 - 110 000; Plein temps

Avantages offerts par ce poste

Relocation support

Sponsorship for exceptional candidates

Résumé du poste

BioTalent in the United Kingdom is seeking a Senior Scientist to drive automated sequencing diagnostics for an infectious disease platform. The role blends molecular biology, engineering, chemistry and automation to translate lab workflows into integrated automated systems from concept to prototype.

You will lead DoE-driven optimisation, collaborate with multi-disciplinary teams and help shape a novel sample-to-answer platform with a focus on robustness and scalability.

Qualifications

• PhD required or equivalent industry experience in molecular biology/biotech.
• Experience developing molecular biology workflows in translational R&D or industrial settings.
• Proven track record automating molecular biology workflows.
• Experience integrating workflows into diagnostic or analytical platforms.

Responsabilités

• Develop and optimise workflows for nucleic acid extraction, purification, library preparation and sample processing.
• Translate manual molecular biology workflows into automated processes for diagnostic platforms.
• Apply DoE and quantitative approaches to optimise system performance.
• Identify bottlenecks and variability across integrated workflows.
• Improve assay robustness, reproducibility and scalability.
• Generate data-driven insights to inform platform design (fluidics, automation, reagents).
• Collaborate with scientists and engineers across disciplines.
• Provide technical leadership and support prototype development.

Connaissances

Molecular biology workflows

Automation & DoE

NGS & sequencing

Data analysis

Cross-disciplinary collaboration

Formation

PhD in Molecular Biology or related field

Outils

Automation platforms

Fluidics systems

Cartridge-based systems

Description du poste

Senior Scientist, Automated Diagnostic Systems

An innovative and well-funded technology organisation is seeking a Senior Scientist to support the development of a next-generation sequencing-based diagnostic platform focused on infectious disease detection.

Working at the intersection of molecular biology, engineering, chemistry and automation, you will play a key role in translating laboratory workflows into integrated automated diagnostic systems. The position offers the opportunity to contribute to the development of a novel sample-to-answer platform from proof of concept through to prototype.

Key Responsibilities

• Develop and optimise workflows for nucleic acid extraction, purification, library preparation and sample processing.
• Translate manual molecular biology workflows into automated processes suitable for diagnostic platforms.
• Apply Design of Experiments (DoE) and quantitative approaches to optimise system performance.
• Identify bottlenecks, variability and failure points across integrated workflows.
• Improve assay robustness, reproducibility and scalability.
• Generate data-driven insights to inform platform design, including fluidics, automation and reagent selection.
• Collaborate closely with scientists and engineers across multiple disciplines.
• Provide technical leadership and support prototype development activities.

Requirements

• PhD, or equivalent industry experience, in Molecular Biology, Biotechnology, Bioengineering, Biochemistry or a related discipline.
• Experience developing molecular biology workflows within industrial or translational R&D environments.
• Proven experience automating or semi-automating molecular biology workflows.
• Experience integrating biological workflows into analytical, diagnostic or cartridge-based platforms.
• Strong understanding of nucleic acid extraction, purification and analysis.
• Experience designing robust experiments and interpreting complex datasets.
• Knowledge of assay performance, reproducibility and development metrics.
• Ability to work effectively within multidisciplinary teams.
• Automated molecular diagnostic platform development.
• Cartridge-based sample preparation systems.
• Diagnostic or analytical instrument development.
• Sequencing library preparation automation.
• NGS, metagenomics or sequencing-based diagnostics.
• Microfluidics and fluid handling technologies.
• Challenging clinical sample preparation workflows.
• Collaboration with software, systems, electrical or mechanical engineering teams.
• Application of Design of Experiments (DoE).

Backgrounds of Interest

• Platform Development
• NGS Workflow Development
• Automated Sample Preparation
• Translational R&D

Relocation support available. Sponsorship may be considered for exceptional candidates