Senior Principal DS Scientist (Drug Substance)

JR United Kingdom; Wrexham; On-site; GBP 60,000 - 100,000; Full time

Job summary

An innovative firm is seeking a Senior Principal Scientist to lead strategic projects in biomanufacturing processes. This role focuses on API/Drug substance processing, where you will develop cutting-edge solutions and ensure compliance with high-quality standards. You will mentor a talented team, oversee advanced projects, and foster innovation by implementing new methodologies. Join a dynamic environment that values collaboration and continuous improvement, making a significant impact in the pharmaceutical industry.

Qualifications

• Expertise in bioprocesses and strong leadership skills.
• In-depth knowledge of CMC development and regulatory requirements.

Responsibilities

• Lead biomanufacturing processes and mentor a team of scientists.
• Design analytical strategies for API/Drug substance processes.

Skills

MS&T bioprocesses

Fermentation

Purification

Chromatography

Filtration

Leadership

CMC development

Regulatory compliance

Innovation

Collaboration

Job description

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Senior Principal DS Scientist (Drug Substance), wrexham

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Client:

Proclinical Staffing

Location:

wrexham, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

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Job Views:

2

Posted:

02.05.2025

Expiry Date:

16.06.2025

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Job Description:

Senior Principal DS Scientist - Permanent - Wrexham, UK

Proclinical is seeking a Senior Principal Scientist to lead strategic projects in biomanufacturing processes, focusing on API/Drug substance processing. This role involves developing innovative solutions for upstream and downstream strategies, ensuring high standards of quality and efficiency. You will serve as the scientific leader for API/Drug substance manufacturing and lead the Purification Chromatography Community of Practice.

Responsibilities:

• Lead and manage biomanufacturing processes, including upstream and downstream strategies.
• Mentor and develop a team of scientists, structuring their work for superior performance.
• Oversee advanced projects, ensuring timelines, budgets, and quality standards are met.
• Design and implement analytical and process characterization strategies for API/DS processes.
• Foster innovation by encouraging new methodologies and technologies.
• Ensure compliance with regulatory guidelines and prepare teams for successful inspections.
• Collaborate with internal stakeholders and external vendors to ensure project success.

Skills & Requirements:

• Expertise in MS&T bioprocesses, including fermentation, purification, chromatography, and filtration.
• Proven leadership skills in managing multidisciplinary scientific teams.
• In-depth knowledge of CMC development and global regulatory requirements.
• Experience in driving innovation and continuous improvement initiatives.
• Strong collaboration and communication skills with internal and external stakeholders.
• Ability to align technical programs with business objectives and manage budgets and timelines.

If you are having difficulty in applying or if you have any questions, please contact Ruhee Saleh at [emailprotected] .

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.