Senior Principal Biostatistician

ICON; Reading; On-site; GBP 90,000 - 120,000; Full time

Benefits offered by this job

Health insurance

Retirement planning

Employee Assistance Programme (LifeWor

Life assurance

Job summary

ICON is a global healthcare intelligence and clinical research organisation dedicated to bringing new medicines and treatments to patients faster. A Senior Principal Biostatistician will lead statistical methodologies, design and analyze clinical studies, and ensure data integrity and regulatory compliance.

You will oversee biostatistics workstreams, mentor junior statisticians, and collaborate with cross-functional teams to drive study execution and scientific transparency.

Qualifications

• Master's degree or Ph.D. in Biostatistics, Statistics, or a related field.
• Extensive experience in biostatistics within the pharmaceutical or biotech industry, particularly in clinical trial design and analysis.
• Strong knowledge of statistical software (e.g., SAS, R) and proficiency in programming for data analysis.
• Excellent problem-solving skills, with the ability to interpret complex data and provide actionable insights.
• Demonstrated leadership abilities, with experience in mentoring and guiding teams.
• Strong communication skills, with the ability to present statistical concepts to non-statistical audiences effectively.
• Detail-oriented, with excellent organizational skills to manage multiple projects and meet deadlines in a fast-paced environment.

Responsibilities

• Designing and implementing statistical analysis plans for clinical trials, ensuring alignment with study objectives and regulatory guidelines.
• Overseeing the statistical analysis of clinical data, providing insights and interpretations to support decision-making and reporting.
• Collaborating with cross-functional teams, including clinical, regulatory, and data management, to ensure integrated and efficient study execution.
• Mentoring junior statisticians and providing training on statistical methodologies and software applications.
• Contributing to the preparation of regulatory submissions and publications, ensuring statistical rigor and transparency.
• Staying updated on industry trends and advancements in statistical methodologies to drive innovation in study design and analysis.
• Participating in protocol development and providing input on endpoints and statistical considerations for clinical studies.

Skills

Biostatistics expertise

Leadership

Communication

Problem-solving

Mentoring

Education

Master's degree or Ph.D. in Biostatistics or related field

Tools

SAS

R

Job description

Senior Principal Biostatistician

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

As a Senior Principal Biostatistician at ICON, you will be responsible for leading statistical methodologies and contribute to the design and analysis of clinical studies to ensure the highest standards of data integrity and regulatory compliance.

What You Will Do:

You will oversee biostatistics workstreams, ensuring deliverables meet quality and timeline expectations. Key responsibilities include:

• Designing and implementing statistical analysis plans for clinical trials, ensuring alignment with study objectives and regulatory guidelines.
• Overseeing the statistical analysis of clinical data, providing insights and interpretations to support decision-making and reporting.
• Collaborating with cross-functional teams, including clinical, regulatory, and data management, to ensure integrated and efficient study execution.
• Mentoring junior statisticians and providing training on statistical methodologies and software applications.
• Contributing to the preparation of regulatory submissions and publications, ensuring statistical rigor and transparency.
• Staying updated on industry trends and advancements in statistical methodologies to drive innovation in study design and analysis.
• Participating in protocol development and providing input on endpoints and statistical considerations for clinical studies.

Your Profile:

You will have solid biostatistics experience, with the ability to manage competing priorities and develop your team. Required qualifications and experience:

• A master's degree or Ph.D. in Biostatistics, Statistics, or a related field.
• Extensive experience in biostatistics within the pharmaceutical or biotech industry, particularly in clinical trial design and analysis.
• Strong knowledge of statistical software (e.g., SAS, R) and proficiency in programming for data analysis.
• Excellent problem-solving skills, with the ability to interpret complex data and provide actionable insights.
• Demonstrated leadership abilities, with experience in mentoring and guiding teams.
• Strong communication skills, with the ability to present statistical concepts to non-statistical audiences effectively.
• Detail-oriented, with excellent organizational skills to manage multiple projects and meet deadlines in a fast-paced environment.

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request.