Senior Statistical Analyst

ICON; Reading; On-site; GBP 75,000 - 110,000; Full time

Benefits offered by this job

Annual leave

Health insurance

Life assurance

Employee assistance

Job summary

ICON is a global healthcare intelligence and clinical research organisation seeking a Senior Statistical Analyst to join the Real World Evidence (RWE) team in Reading. You will design and analyze observational studies, develop SAPs, and produce robust statistical outputs for reports and publications.

The role emphasizes SAS programming, advanced statistical methods, and collaboration with clients and cross-functional teams to deliver high‑quality evidence for healthcare decision-making.

Qualifications

• Master's degree or PhD in Statistics, Biostatistics, Epidemiology, Mathematics, Data Science, Public Health, or related quantitative discipline.
• Significant experience in pharmaceutical/healthcare or Real World Evidence environments.
• Advanced SAS programming experience with datasets, analyses, macros, tables, listings and figures.
• Strong understanding of statistical methodologies and their application to healthcare data.
• Experience developing Statistical Analysis Plans (SAPs) and analysis specifications.
• Knowledge of observational study design and health outcomes research is desirable.
• Experience with regression modelling, survival analysis, repeated measures, and other advanced methods.
• Strong written and verbal communication skills for technical and non‑technical audiences.

Responsibilities

• Support study conception, design and protocol development for real-world evidence projects.
• Develop SAPs and analysis specifications; perform sample size and power calculations.
• Write methods sections and develop analysis plans; create datasets and programs in SAS.
• Produce tables, listings, figures and visualizations for client deliverables.
• Lead quality control and validation of data, variables and analyses.
• Collaborate with multidisciplinary teams and communicate statistical requirements to clients.

Skills

SAS programming

Statistical analysis

Survival analysis

Longitudinal analysis

Data management

Communication skills

Education

Master's or PhD in Statistics

Tools

R language

Job description

JR158816 Senior Statistical Analyst

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

Senior Statistical Analyst - Real World Evidence

We are currently seeking a Senior Statistical Analyst to join our Real World Evidence (RWE) team. This position offers an exciting opportunity to work on observational research studies, real-world data analyses, health outcomes research, and epidemiology projects that help generate evidence to support healthcare decision-making.

As a Senior Statistical Analyst, you will play a key role throughout the project lifecycle, from study design and statistical planning through to analysis, reporting, publication and client interaction. The role requires strong technical expertise in SAS programming, statistical methodology, and the interpretation of complex healthcare datasets.

What You Will Be Doing

• Support study conception, design, and protocol development for real-world evidence and observational research projects.
• Contribute to study start-up activities, including review and development of protocols, case report forms, and statistical methodologies.
• Write statistical methods sections of study protocols and develop statistical analysis plans.
• Perform sample size and power calculations.
• Review database specifications and participate in data review activities.
• Develop table, listing and figure shells and programming specifications.
• Lead the review and validation of raw and derived variables.
• Create and maintain derived datasets using SAS programming.
• Conduct statistical analyses using appropriate methodologies, including advanced and specialized statistical techniques such as longitudinal analyses, repeated measures, survival analyses, and other complex modelling approaches.
• Develop and validate SAS programs, macros, tables, listings, figures, and project deliverables.
• Lead quality control activities throughout programming and analysis processes.
• Manage and review internal and external data transfers.
• Produce project reports, statistical outputs, visualizations, tables and graphs for client delivery.
• Contribute to manuscripts, abstracts, conference presentations and peer-reviewed publications.
• Write methods and results sections for final reports and scientific publications.
• Communicate directly with clients, investigators and cross-functional teams regarding project deliverables and statistical requirements.
• Represent Statistical Analysis in proposal development and RFP activities.
• Participate in department initiatives, process improvements, SOP development and training activities.
• Deliver internal technical presentations and contribute to knowledge sharing within the team.
• Attend departmental meetings and support broader Real World Evidence research activities.

Your Profile

To be successful in this role, you will possess a strong statistical and programming background, together with experience working with healthcare, clinical, observational or real-world data.

Required Qualifications and Experience:

• Master's degree or PhD in Statistics, Biostatistics, Epidemiology, Mathematics, Data Science, Public Health, or a related quantitative discipline.
• Significant experience within the pharmaceutical, biotechnology, CRO, healthcare research, or Real World Evidence environment.
• Advanced SAS programming experience is essential, including development of datasets, statistical analyses, macros, tables, listings and figures.
• Strong understanding of statistical methodologies and their practical application to healthcare and observational data.
• Experience developing Statistical Analysis Plans (SAPs) and analysis specifications.
• Knowledge of observational study design, epidemiology, health outcomes research, registries, claims databases, electronic health records, or other real-world data sources is highly desirable.
• Experience applying statistical techniques such as regression modelling, survival analysis, repeated measures analysis and other advanced methods.
• Ability to independently manage statistical deliverables while collaborating effectively within multidisciplinary teams.
• Strong written and verbal communication skills with the ability to explain complex statistical concepts to both technical and non-technical audiences.
• Preferred Experience:
• Experience within a Real World Evidence, Health Economics & Outcomes Research (HEOR), Epidemiology, or Data Analytics team.
• Experience authoring publications, abstracts, or conference presentations.
• Proficiency in additional programming languages such as R is advantageous.

Why Join the Real World Evidence Team?

You will be part of a collaborative team delivering high-impact research that helps shape healthcare decisions and improve patient outcomes globally. This role provides the opportunity to work on diverse, scientifically rigorous projects while developing deep expertise in real-world data, advanced analytics and evidence generation.

Please note: Strong SAS programming experience is a core requirement for this position and will be a key focus throughout the selection process.

#LI-SA1

What ICON can offer you:

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here