Senior Principal Biostatistician - Lead Trial Statistics

ICON; Reading; On-site; GBP 90,000 - 120,000; Full time

Benefits offered by this job

Health insurance

Retirement planning

Employee Assistance Programme (LifeWor

Life assurance

Job summary

ICON is a global healthcare intelligence and clinical research organisation dedicated to bringing new medicines and treatments to patients faster. A Senior Principal Biostatistician will lead statistical methodologies, design and analyze clinical studies, and ensure data integrity and regulatory compliance.

You will oversee biostatistics workstreams, mentor junior statisticians, and collaborate with cross-functional teams to drive study execution and scientific transparency.

Qualifications

• Master's degree or Ph.D. in Biostatistics, Statistics, or a related field.
• Extensive experience in biostatistics within the pharmaceutical or biotech industry, particularly in clinical trial design and analysis.
• Strong knowledge of statistical software (e.g., SAS, R) and proficiency in programming for data analysis.
• Excellent problem-solving skills, with the ability to interpret complex data and provide actionable insights.
• Demonstrated leadership abilities, with experience in mentoring and guiding teams.
• Strong communication skills, with the ability to present statistical concepts to non-statistical audiences effectively.
• Detail-oriented, with excellent organizational skills to manage multiple projects and meet deadlines in a fast-paced environment.

Responsibilities

• Designing and implementing statistical analysis plans for clinical trials, ensuring alignment with study objectives and regulatory guidelines.
• Overseeing the statistical analysis of clinical data, providing insights and interpretations to support decision-making and reporting.
• Collaborating with cross-functional teams, including clinical, regulatory, and data management, to ensure integrated and efficient study execution.
• Mentoring junior statisticians and providing training on statistical methodologies and software applications.
• Contributing to the preparation of regulatory submissions and publications, ensuring statistical rigor and transparency.
• Staying updated on industry trends and advancements in statistical methodologies to drive innovation in study design and analysis.
• Participating in protocol development and providing input on endpoints and statistical considerations for clinical studies.

Skills

Biostatistics expertise

Leadership

Communication

Problem-solving

Mentoring

Education

Master's degree or Ph.D. in Biostatistics or related field

Tools

SAS

R

Job description

ICON is a global healthcare intelligence and clinical research organisation dedicated to bringing new medicines and treatments to patients faster. A Senior Principal Biostatistician will lead statistical methodologies, design and analyze clinical studies, and ensure data integrity and regulatory compliance.

You will oversee biostatistics workstreams, mentor junior statisticians, and collaborate with cross-functional teams to drive study execution and scientific transparency.