Senior Medical Director

AL Solutions; Cambridge; On-site; GBP 100,000 - 150,000; Full time

Job summary

A leading clinical-stage Biotech in Cambridge is seeking a Senior Medical Director to oversee global trials and regulatory strategies. This pivotal role demands strong leadership and collaboration skills, ensuring compliance and driving clinical development forward in a fast-paced environment.

Qualifications

• 10+ years of experience in clinical development with a strong focus on Phase 3 programs.
• Proven track record of leading global trials and interfacing with regulatory agencies (FDA/EMA).

Responsibilities

• Lead the medical content and strategy across late-phase development programs.
• Provide clinical and scientific leadership to internal teams and external partners.
• Ensure robust medical oversight of studies and safety data.

Skills

Leadership

Collaboration

Strategic Thinking

Communication

Education

Qualified physician (GMC registered or eligible)

Job description

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Expert in linking Biometrics, Biologics and CMC Professionals to Biotech and CDMOs throughout the United States and Canada.

Position: Senior Medical Director

Location: Cambridge, United Kingdom

George Higginson is currently searching for an experienced Senior Medical Director to play a pivotal leadership role in advancing a Clinical-stage Biotech's clinical development programs through late-stage development. Reporting to the Chief Medical Officer, you’ll provide medical oversight across global trials, contribute to regulatory strategy, and ensure GCP compliance throughout. This is a high-impact role for a strategic clinical leader who thrives in a fast-paced, cross-functional environment.

Main Responsibilities:

• Lead the medical content and strategy across late-phase development programs.
• Provide clinical and scientific leadership to internal teams and external partners (e.g. CROs, consultants).
• Ensure robust medical oversight of studies and safety data, in collaboration with PV and Clinical Operations.
• Act as a key contributor to regulatory submissions (NDA/BLA) and represent the company in Health Authority meetings.
• Serve as deputy to the CMO when required, and a core member of the Drug Safety Committee.
• Oversee medical input on protocol design, study conduct, data review, and benefit-risk assessments.
• Collaborate closely with Medical Affairs and Commercial to align clinical strategy with broader goals.
• Recruit, lead, and develop high-performing medical staff as needed.

Requirements:

• Qualified physician (GMC registered or eligible).
• 10+ years of experience in clinical development with a strong focus on Phase 3 programs.
• Proven track record of leading global trials and interfacing with regulatory agencies (FDA/EMA).
• Strong knowledge of GCP, ICH guidelines, and pharmacovigilance.
• Skilled at interpreting complex data and making informed, strategic decisions.
• Experienced in matrix leadership and cross-functional collaboration.

'Nice-to-haves':

• Background in Dermatology or Rheumatology.
• Experience with Biologics and/or Immunology.
• Prior involvement in NDA/BLA or MAA submissions.

What We’re Looking For:

• A strategic thinker with a strong scientific foundation and operational awareness.
• A collaborative leader and effective communicator, comfortable operating at executive level.
• A hands-on contributor who can switch seamlessly between big-picture planning and day-to-day execution.

This is a fantastic opportunity to be a key part of a true-underdog clinical-stage Biotech, soon approaching a BLA submission.

Apply today to take the next step in your leadership journey!

Seniority level

• Seniority level

  Director

Employment type

• Employment type

  Full-time

Job function

• Job function

  Science, Research, and Analyst

• Industries

  Staffing and Recruiting, Biotechnology Research, and Pharmaceutical Manufacturing

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