Senior Manager, Study Oversight Manager

Amgen; Cambridge; On-site; GBP 90,000 - 140,000; Full time

Benefits offered by this job

Career growth

Inclusion

Total rewards

Job summary

Amgen in Cambridge, United Kingdom, is seeking a Senior Manager Study Oversight to provide strategic oversight of FSP resources and performance at country level, ensuring high-quality clinical trial delivery. You will drive collaboration, supplier performance, issue resolution, and mentor Study Oversight Managers.

We expect extensive trial experience, CRO management, and strong regulatory knowledge to lead governance and ensure effective operations across regions.

Qualifications

• Degree educated with significant clinical execution experience.
• Experience leading people, teams, projects, or programs within a clinical research environment.
• Strong life sciences/biopharma clinical trial experience, within biotech, pharma, or CRO environments.
• Experience managing CROs and other clinical research vendors.
• Experience overseeing clinical operations across countries/regions with knowledge of local regulations and compliance.
• Proven management of study timelines, budgets, KPIs, enrollment, quality, and operational risks.
• Ability to lead, mentor, train, and develop cross-functional clinical teams.
• Experience supporting study start-up, site readiness, audits, inspections, and regulatory requirements.
• Understanding of EDC, data integrity, and query management.
• Strong communication, stakeholder and risk management skills across functions, suppliers, geographies, and senior leadership.
• Continuous improvement mindset with the ability to drive monitoring excellence.

Responsibilities

• Lead oversight of FSP resources, capacity, performance, quality, and delivery from study start-up through close-out.
• Monitor key metrics, milestones, and quality targets, proactively addressing performance or delivery risks.
• Serve as an escalation point for supplier-related issues and communicate country-level trends and challenges to senior leadership.
• Lead governance and strengthen collaboration across FSPs, study teams, sites, and global stakeholders.
• Mentor and develop Study Oversight Managers, driving consistency and effective ways of working.
• Partner with Local Study Operations leadership to ensure appropriate staff and site oversight.
• Support inspection readiness, audits, regulatory inspections, and investigator site relationships.
• Drive continuous improvement initiatives to enhance operational efficiency, supplier engagement, and trial delivery.

Skills

People leadership

Clinical trials

Vendor management

CRO experience

Regulatory knowledge

Budget & timelines

Stakeholder management

Education

Degree in life sciences

Job description

If you feel like you’re part of something bigger, it’s because you are. At Amgen our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

Senior Manager Study Oversight

In this vital role you will provide strategic oversight of Functional Service Provider (FSP) resources and performance at the country level, ensuring high-quality and compliant clinical trial delivery. You will drive cross-functional collaboration, supplier performance, issue resolution, and continuous improvement while developing and mentoring Study Oversight Managers.

• Lead oversight of FSP resources, capacity, performance, quality, and delivery from study start-up through close-out.
• Monitor key metrics, milestones, and quality targets, proactively addressing performance or delivery risks.
• Serve as an escalation point for supplier-related issues and communicate country-level trends and challenges to senior leadership.
• Lead governance and strengthen collaboration across FSPs, study teams, sites, and global stakeholders.
• Mentor and develop Study Oversight Managers, driving consistency and effective ways of working.
• Partner with Local Study Operations leadership to ensure appropriate staff and site oversight.
• Support inspection readiness, audits, regulatory inspections, and investigator site relationships.
• Drive continuous improvement initiatives to enhance operational efficiency, supplier engagement, and trial delivery.

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. What we seek in you as an experienced professional, are these qualifications and skills:

• Degree educated with significant clinical execution experience.
• Experience leading people, teams, projects, or programs within a clinical research environment.
• Strong life sciences/biopharma clinical trial experience, within biotech, pharma, or CRO environments.
• Experience managing CROs and other clinical research vendors.
• Experience overseeing clinical operations across countries/regions with knowledge of local regulations and compliance.
• Proven management of study timelines, budgets, KPIs, enrollment, quality, and operational risks.
• Ability to lead, mentor, train, and develop cross-functional clinical teams.
• Experience supporting study start-up, site readiness, audits, inspections, and regulatory requirements.
• Understanding of EDC, data integrity, and query management.
• Strong communication, stakeholder and risk management skills across functions, suppliers, geographies, and senior leadership.
• Continuous improvement mindset with the ability to drive monitoring excellence.

What You Can Expect Of Us

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

• Vast opportunities to learn and move up and across our global organization
• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Application due date: 31st of August 2026

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.