Senior Global Clinical Study Lead — Cross‑Functional & CRO Oversight

KPS Life; Uxbridge; Hybrid; GBP 90,000 - 120,000; Full time

Job summary

KPS Life in the United Kingdom is seeking a Senior Clinical Study Lead to drive the delivery of large, global clinical trials from protocol development through study close-out. You will lead cross-functional study teams and act as the primary contact for study oversight, accountable for timelines, budget, quality, and ensuring ICH/GCP compliance, whether studies are run in-house or outsourced to CROs.

This sponsor-dedicated role requires 3 days in the Uxbridge office, with up to 25% travel.

Qualifications

• Bachelor’s degree and 8+ years in clinical trials; global study leadership.
• Proven experience managing CROs/vendors and regulatory compliance.
• Strong project management and cross-functional collaboration.
• Experience with CTMS, EDC, IWRS/IVRS, and MS Project.

Responsibilities

• Lead cross-functional teams and oversee end-to-end study execution.
• Provide input into protocol development and key study documents (CRF, monitoring plan, SAP).
• Manage study systems (CTMS, TMF) and ensure registry compliance.
• Lead vendor selection, contracting and oversight.
• Drive site selection, activation, recruitment & retention strategies.
• Monitor data quality, timelines and budget; escalate issues with mitigation plans.
• Ensure inspection readiness and support audits/CAPAs.
• Oversee study close-out activities including database lock and TMF reconciliation.

Skills

Cross-functional leadership

Study management

Regulatory knowledge

CTMS/EDC/IWRS

MS Project

Budget management

Communication

Travel readiness

Education

Bachelor’s degree

Tools

CTMS

EDC

IWRS/IVRS

MS Project

Job description

KPS Life in the United Kingdom is seeking a Senior Clinical Study Lead to drive the delivery of large, global clinical trials from protocol development through study close-out. You will lead cross-functional study teams and act as the primary contact for study oversight, accountable for timelines, budget, quality, and ensuring ICH/GCP compliance, whether studies are run in-house or outsourced to CROs.

This sponsor-dedicated role requires 3 days in the Uxbridge office, with up to 25% travel.