Senior AI-Driven Genomic Medicine Translational Fellow

University of Southampton; England; On-site; GBP 55,000 - 75,000; Full time

Benefits offered by this job

Athena SWAN principles

Flexible and part-time working options

Pension scheme

Job summary

University of Southampton invites applications for a full-time, fixed-term Senior Research Fellow in AI Applied to Genomic Medicine, based at the University Hospital Southampton site. You will lead translational research integrating clinical and genomic data to improve genomic diagnostics for autoimmune disease and develop robust LLM-based data pipelines.

You will manage early career researchers, collaborate with multidisciplinary teams, and contribute to education and training in genomic data

Qualifications

• PhD in health informatics, bioinformatics, genomics, computational biology, data science, or closely related field.
• Extensive experience integrating genomic data with structured clinical or phenotypic data and familiarity with clinical ontologies such as HPO, SNOMED CT and ICD-10.
• Hands-on experience with open-source large language models, EHR data extraction, high-throughput sequencing data analysis, and bioinformatics workflows used in research and/or diagnostic settings.
• Strong programming skills (Python, R, Perl, C/C++, Bash) and confidence working across Linux and other operating systems.
• Experience with ontology management software and data governance for handling sensitive EHR, genomic, and clinical data.
• Excellent communication and interpersonal skills to collaborate across disciplines and convey complex concepts.

Responsibilities

• Lead a project extracting structured clinical findings from EHRs using open-source LLMs and harmonise findings to clinically relevant ontologies.
• Drive translational research integrating clinical and genomic data to advance personalized diagnostics.
• Develop, implement and maintain robust, reproducible LLM-based pipelines with modern workflow systems and HPC.
• Produce rigorous research outputs to advance genomic diagnostics and grow your research profile.
• Contribute to education and training in genomic data science for academic and clinical audiences.
• Effectively manage early career researchers in planning and delivery of project objectives.
• Collaborate with local and international colleagues across genomics, medicine, data science, statistics, software engineering and compute infrastructure.

Skills

Python

R

C/C++

Bash

Bioinformatics workflows

Data governance

Communication

Project management

Education

PhD in health informatics, bioinformatics, genomics, computational biology, data science, or related field

Tools

Ontology management software

IRIDIS HPC

EHR data extraction tools

Open-source LLMs

Job description

University of Southampton invites applications for a full-time, fixed-term Senior Research Fellow in AI Applied to Genomic Medicine, based at the University Hospital Southampton site. You will lead translational research integrating clinical and genomic data to improve genomic diagnostics for autoimmune disease and develop robust LLM-based data pipelines.

You will manage early career researchers, collaborate with multidisciplinary teams, and contribute to education and training in genomic data