Scientist, Mouse Models

Priora; Greater London; On-site; GBP 45,000 - 65,000; Full time

Benefits offered by this job

Competitive salary

Pension contribution

Gym membership support

Share option scheme

Job summary

Priora seeks an experienced in vivo scientist to lead preclinical mouse studies at a London off-site vivarium. You will execute dosing, biodistribution, tissue collection, histology and behavioural assessments, ensuring robust, reproducible workflows and strong scientific integrity.

You will work with the in vivo team to own study execution, troubleshoot procedures, and align work with programme goals while upholding high animal welfare and regulatory standards.

Qualifications

• Hold a PhD in immunology or a related field; Master’s with equivalent experience considered.
• Current UK Home Office PIL (A/B/C) preferred.
• Experience dosing mice and collecting tissue in the last two years.

Responsibilities

• Run mouse studies, including IV and intracerebral dosing.
• Carry out biodistribution studies across multiple organs.
• Process tissue and deliver histological endpoints.
• Perform behavioural assessments to support studies.
• Maintain thorough documentation and regulatory compliance.

Skills

Mouse handling

In vivo procedures

Immunohistochemistry

Perfusions

Behavioural assays in rodents

Dosing techniques (IV, intracerebral)

UK Home Office PIL

Study documentation

Education

PhD in immunology or related field

Master's degree considered with equivalent experience

Tools

qPCR biodistribution analysis

Bioluminescence imaging (IVIS)

Flow cytometry

Job description

Organisation/Company Priora Research Field Biological sciences Researcher Profile First Stage Researcher (R1) Positions Other Positions Application Deadline 19 Oct 2026 - 00:00 (Africa/Abidjan) Country United Kingdom Type of Contract Permanent Job Status Full-time Hours Per Week 40 Offer Starting Date 19 Oct 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

About the role

We are looking for an experienced in vivo scientist to play a central role in the execution and development of our preclinical mouse studies.

Working closely with our in vivo team, you will take responsibility for the practical delivery of studies across dosing, biodistribution, tissue collection, histology and behavioural assessment. Our animal work is conducted at an off-site vivarium in London, where you will help establish and maintain rigorous, reproducible experimental workflows.

This is a highly hands-on scientific role. You will execute complex in vivo studies, troubleshoot experimental procedures, ensure appropriate controls and documentation, and contribute to the interpretation of resulting datasets. You will also work with the wider scientific team to refine methods and ensure that animal studies are aligned with the broader objectives of the programme.

The quality and reproducibility of our in vivo data are critical to programme progression. You will therefore play an important role in ensuring that studies are conducted to high scientific, ethical and regulatory standards, and that the resulting samples and datasets are suitable for downstream analysis and decision-making.

The role would suit a scientist with strong practical expertise in rodent experimentation who is methodical, technically confident and comfortable taking substantial ownership of study execution within a multidisciplinary research environment.

Responsibilities include:

• Run mouse studies, including dosing by intravenous and intracerebral routes
• Carry out biodistribution studies, collecting tissue across multiple organs
• Process tissue and deliver the histological endpoints
• Carry out the behavioural assessments that support each study
• Keep the animal work well documented, well controlled and compliant

You may be a good fit if you:

• Hold a PhD in immunology or a related field, such as bioscience or cell biology. Exceptional candidates with a Master's degree and equivalent experience will also be considered
• Hold a current UK Home Office personal licence (PIL A/B/C)
• Have personally dosed mice and collected tissue within the last two years
• Are experienced in mouse handling and regulated in vivo procedures
• Do your own perfusions and immunohistochemistry
• Have run behavioural assays in rodents

Strong candidates may also have experience with:

• Dissociating tissue and analysing it by flow cytometry
• Culturing primary neurons
• qPCR biodistribution analysis
• Bioluminescence imaging (IVIS)
• Working in an off-site or contract vivarium

Salary and other benefits

Highly competitive salary and pension contribution, alongside a wellness and lifestyle package that includes support towards gym membership and living close to the lab. All employees participate in the company share option scheme.

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