Scientist I

Evote; Abingdon; On-site; GBP 35,000 - 50,000; Full time

Job summary

Evotec in Abingdon, Oxfordshire, is seeking a Scientist I on a Temporary Fixed Term Contract. You will execute approved work plans in the protein science area and deliver results to project specifications.

Key responsibilities include designing, cloning, and optimizing expression constructs; conducting expression experiments across systems (E. coli, insect, mammalian); assessing quality via SDS-PAGE and Western blot; and collaborating across multiple projects while following training and

Qualifications

• PhD or Degree with corresponding experience in a relevant scientific discipline.

Responsibilities

• Execution of approved work plans for early drug discovery projects.
• Provide recommendations for improving work plans for review and approval by Grade 5 or above.
• Support more than one project across modalities and therapeutic areas.
• Deliver timely, accurate results of pre-agreed quality to project specifications.
• May perform data analysis and share results with internal or external customers.

Skills

Protein expression

Construct design

Expression testing

Protein analysis

Troubleshooting

Independent work

Education

PhD or Degree in relevant science

Tools

E. coli expression

Insect expression (Baculovirus/S2)

Mammalian expression

SDS-PAGE & Western blot

Job description

We are currently recruiting for a Scientist I to join our Team in Abingdon, Oxfordshire on a Temporary Fixed Term Contract. Responsible execution of work plans for their protein science area. Accountable for delivery from early drug discovery workflows in their area of expertise.

Role: Scientist I

Role Type: TemporaryFixed Term Contract

Hours: Full time, 40 hours per week, Monday to Friday

Location: Hybrid, Abingdon, Oxfordshire

Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies

Key Accountabilities

• Execution of approved work plans in early drug discovery projects.
• Provide recommendations for improving Workplans for review and approved by Grade 5 or above
• Responsible for supporting more than one project across modalities and therapeutic areas
• Will be expected to deliver timely, accurate results of pre-agreed quality to project specifications.
• May conduct some data analysis ahead of internal review prior to release to internal or external customers.

Knowledge & Experience

• Technical knowledge of protein expression with a proven ability to deliver results across target families within agreed timelines and budget, meeting agreed quality criteria.

• Design, clone, and optimise expression constructs for recombinant protein production in E.coli, insect (Baculovirus and S2), and mammalian systems.
• Execute small‑ to large‑scale expression experiments to maximise yield, solubility, and functionality.
• Assess quality via SDS‑PAGE, Western blot, and related analytics.
• Troubleshoot complex expression challenges with creative, data‑driven solutions.

• Understanding of scientific and technical background of experiments.
• Experience of precise execution of workplans.
• Expected to have some independence, making day-to-day technical decisions
• Expected to follow training provided on the correct use and maintenance of lab. equipment

Education and Qualifications

• A PhD or a Degree with corresponding experience in a relevant scientific discipline ideally with relevant experience in industry.

Evotec Leadership Competencies

Limited Research: Relies on readily available information and is encouraged to explore more thorough research and analysis

Reactive Approach: Addresses challenges as they arise; in the process of learning to anticipate potential issues; working towards a more proactive approach

Some Initiative: Shows a willingness to learn about driving outcomes but often benefits from guidance and support

Reactive Service: Responds to customer issues when prompted, rather providing short-term solutions

Developing Information Sharing: Occasionally shares information when prompted; learning the importance of open communication

Emerging Team Engagement: Shows some effort in engaging with team members, working on giving interactions more depth

Reactive Problem-Solving: Reliably addresses issues as they arise, starting to learn the importance of proactive planning and anticipation

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.