Scientist 2/ Senior Scientist 1 - Electrophysiology (FTC)

Sygnature Discovery; Glasgow; On-site; GBP 36,000 - 48,000; Full time

Benefits offered by this job

25 days annual leave

Private Medical Insurance

Life Insurance

Employee Assistance Programme

Enhanced Family Friendly Policies

Sygnature Group Pension Scheme

1 paid volunteer day per year

Job summary

Sygnature Discovery in Glasgow is seeking an Electrophysiologist scientist to design, optimise and execute cell‑based ion channel assays using automated or manual electrophysiology platforms, supporting our growing discovery programmes.

You will work across a diverse client portfolio, generate high‑quality functional data, and contribute to scientific insight that shapes early drug discovery decisions on a 1-year fixed term contract.

Qualifications

• BSc in Biology or related life science field.
• Hands-on ion channel research experience.
• Experience with automated or manual electrophysiology platforms.
• Understanding of mammalian cell biology and plate-based functional assays.
• Strong problem-solving skills and collaborative spirit.

Responsibilities

• Apply patch-clamp electrophysiology to support assay development, hit validation and lead optimisation.
• Develop, validate and execute cell-based ion channel assays using recombinant expression systems.
• Contribute to expansion of the assay portfolio by implementing new technologies.
• Support day-to-day lab operations, including cell culture, reagent prep and equipment maintenance.
• Communicate findings through oral presentations and written reports to internal teams and external partners.

Skills

Ion channel research

Patch-clamp electrophysiology

Cell culture

Data analysis

Collaborative work

Education

BSc in Biology

Tools

Electrophysiology equipment

Job description

About Sygnature Discovery

At Sygnature Discovery, we create exceptional scientific outcomes. For our customers, who bring life-changing medicines to patients; and for our people, who help make this possible.

We’re 700+ scientists from over 50 countries, working as one across Europe and North America. With no competing internal programs, we offer total confidentiality and commitment.

Over the past 20 years, we’ve earned a track record of real impact: 60+ advanced candidates, 250 patents filed, 200+ active projects. Over 90% of our customers choose to stay with us – from biotechs racing to clinic to pharma companies that need specialised expertise for targeted challenges.

About the role:

As demand for our ion channel capabilities continues to grow, we are expanding our electrophysiology group in Glasgow and are seeking an experienced scientists to contribute to cutting‑edge discovery programmes. Please note that this is is 1 year Fixed Term Contract.

As Electrophysiologist scientist, you will play a central role in the design, optimisation, and execution of cell‑based ion channel assays using automated or manual electrophysiology platforms. You will work across a diverse portfolio of client projects, generating high‑quality functional data and contributing to scientific insight that shapes early drug discovery decisions.

Role Responsibilities:

• Apply automated or manual patch‑clamp electrophysiology to support assay development, hit validation, and lead optimisation.
• Develop, validate, and execute cell‑based ion channel assays using recombinant expression systems.
• Contribute to the expansion of the company’s assay portfolio by implementing new technologies and methodologies.
• Support day‑to‑day laboratory operations, including cell culture, reagent preparation, and equipment maintenance.
• Communicate scientific findings through clear oral presentations and written reports to internal teams and external partners.

Skills & Qualifications:

• BSc in Biology or a related life science discipline.
• Hands‑on experience in ion channel research, ideally using recombinant mammalian cell lines.
• Practical knowledge of electrophysiology techniques; experience with automated or manual platforms (including two electrode voltage clamp) is highly advantageous.
• Understanding of mammalian cell biology, plate based functional assays, liquid handling automation, and pharmacological data analysis.
• Strong problem‑solving skills, scientific curiosity, and the ability to independently deliver complex experimental work while contributing to a collaborative team environment.

Benefits

25 days annual leave (plus bank holidays)

Private Medical Insurance

Life Insurance

Employee Assistance Programme

Enhanced Family Friendly Policies

Sygnature Group Pension Scheme

1 paid volunteer day per year