Research Associate

Instruct-ERIC; Greater London; Hybrid; GBP 34,000 - 50,000; Full time

Job summary

Imperial College London in London invites applications for a Research Associate to join the Centre for Structural Biology in the Department of Life Sciences, working on the structure and mechanism of the AAA ATPase p97. Applicants must hold a PhD in structural biology or biochemistry, with demonstrated capacity for innovative high-quality research.

Experience in X-ray crystallography or electron microscopy single-particle analysis is essential, along with strong biochemistry skills and excellent

Qualifications

• PhD in structural biology or biochemistry with evidence of innovative high-quality research.
• Experience in a structural biology lab with X-ray crystallography or EM single-particle analysis is essential.
• Advanced knowledge of protein biochemistry and structural biology.
• Experience in supervising/training junior staff and writing scientific papers is advantageous.

Responsibilities

• Work on the structure and mechanism of the AAA ATPase p97 within the Centre for Structural Biology.
• Collaborate within a multidisciplinary team and contribute to high-quality publications.

Skills

Teamwork

Written comms

Verbal comms

Problem solving

Education

PhD in structural biology or biochemistry

Tools

X-ray crystallography

Electron microscopy

Job description

Jobs in Structural Biology and Related Fields

Research Associate

Imperial College London, London, United Kingdom

The department wishes to recruit a Research Associate for up to 24months in the first instance with possible extension to up to five years to work in the research group of Professor Paul Freemont and Professor Xiaodong Zhang (http://www.msf.bio.ic.ac.uk/index.php ) in the Centre for Structural Biology, Department of Life Sciences at the South Kensington Campus of Imperial College London.

The research group comprises research fellows, research associates and PhD students from a diverse range of background including molecular biology, biochemistry, X-ray crystallography, electron microscopy, physics and engineering.

Funded by a CRUK programme grant to Professor Paul Freemont and Professor Xiaodong Zhang, you will join a multi-disciplinary group to investigate the structure and mechanism of the AAA ATPase p97. P97 is a versatile participant of the ubiquitin proteasome system, interacting with a larger network of adaptor proteins to mediate a variety of cellular processes including ER associated degradation, autophagy and DNA damage repair.

Successful candidates must hold a PhD in a structural biology or biochemistry discipline or an equivalent level of research, industrial or commercial experience and have demonstrated capacity for innovative high quality structural biological research. Previous research experience in a structural biological laboratory environment covering X-ray crystallography or electron microscopy single particle analysis is essential. The successful candidate must also have an advanced knowledge of protein biochemistry and structural biology. Experience in supervision and training of junior research staff and students and in writing scientific research papers would be advantageous. The successful candidate must be able to work effectively within a team, have the ability to develop and apply new concepts, and have a creative approach to problem-solving. They will also be expected to demonstrate excellent verbal and written communication skills, and be able to write clearly and succinctly for publication.