Postdoctoral Research Associate in Experimental Phasing Analysis

Instruct-ERIC; United Kingdom; Remote; GBP 32,000 - 46,000; Full time

Job summary

Diamond Light Source Ltd. is seeking a Postdoctoral Research Associate to develop tools for automated experiment analysis and phasing of diffraction data sets. The role involves collaboration with the Soleil synchrotron MX team and travel to Soleil 3-4 times yearly.

The ideal candidate will advance crystallographic methods, publish results, and support users in data analysis and experimental design, while working within a multi-disciplinary software and beamline team.

Qualifications

• Degree or equivalent qualification or experience.
• Good interpersonal, communication, organizational and presentational skills.
• Ability to get to the heart of the problem and take it through to completion.
• Ability to work as part of a multi-disciplinary team.
• Ability to work flexibly with occasional weekend and out-of-hours.
• Self motivation.
• Be available to travel occasionally within the UK and abroad, including overnight absences.
• Good working knowledge of scientific programming.
• Experience in macromolecular crystallography data collection and analysis.
• Experience in programming in a high level language (e.g. Python)

Responsibilities

• Working closely with project leader, software teams and beamline staff to develop new approaches to MX experimental phasing analysis.
• Conduct scientific research and development into crystallographic methods under the guidance of the project leader.
• Publish and present research at conferences both in UK and abroad.
• Support users by providing advice and guidance on the best approach to experiments, data analysis and research techniques

Skills

Scientific programming

Python programming

Crystallography knowledge

Interpersonal & communication skills

Travel willingness

Education

Degree or equivalent qualification

Tools

Scientific computing tools

Python

Job description

Jobs in Structural Biology and Related Fields

Postdoctoral Research Associate in Experimental Phasing Analysis

Diamond Light Source Ltd, Harwell Science and Innovation Campus in South Oxfordshire, United Kingdom

Duties

Diamond Light Source is the UK’s national synchrotron science facility. Located at Harwell Science and Innovation Campus in Oxfordshire, we enable world-leading research across a wide range of scientific disciplines and industrial applications.

We are looking for a highly motivated researcher to develop tools for automated experiment analysis and phasing of diffraction data sets using strategies intimately coupled with, and providing feedback to, the data collection protocols used. The candidate will work closely with other developers at Diamond. This work will be carried out in collaboration with the MX team at the Soleil synchrotron and as such will involve travel to Soleil 3-4 times a year for meetings and experiments.

The automatic determination of experimental phases is an essential step towards providing users with structural information and provides an exciting opportunity for an enthusiastic crystallographer with an interest in methods development.

Duties to include:

• Working closely with project leader, software teams and beamline staff to develop new approaches to MX experimental phasing analysis;
• Conduct scientific research and development into crystallographic methods under the guidance of the project leader;
• Publish and present research at conferences both in UK and abroad;
• Support users by providing advice and guidance on the best approach to experiments, data analysis and research techniques

Qualifications and Experience: Essential

• Appropriate degree or equivalent qualification or experience;
• Good interpersonal, communication, organizational and presentational skills;
• Ability and initiative to get to the heart of the problem and take it effectively through to completion;
• Ability to work as part of a multi-disciplinary team;
• Ability to work flexibly with occasional weekend and out-of hours;
• Self motivation;
• Be available to travel occasionally within the UK and abroad, including overnight absences;
• Good working knowledge of scientific programming;
• Experience in macromolecular crystallography data collection and analysis;
• Experience in programming in a high level language (e.g. Python)

Qualifications and Experience: Desirable

• Experience of contributing in a major way to a successful scientific software project;
• Experience in providing expert support to end-users;
• Experience in advanced programming techniques.