Research Assistant in Experimental Pulmonary Hypertension

1000scholars; Greater London; Vor Ort; GBP 45.000 - 49.000; Vollzeit

Zusammenfassung

Imperial College London’s National Heart and Lung Institute invites a motivated Research Assistant to join a BHF-funded project on how the complement system contributes to pulmonary arterial hypertension. Based in the Vascular Sciences Section, you will work across animal models, primary cell culture, molecular biology and omics to understand disease mechanisms.

You will hold a BSc or MSc in Biological Sciences or a related discipline and have hands-on lab experience with qPCR, ELISA, western

Qualifikationen

• The candidate should hold a BSc or MSc in Biological Sciences, Biomedical Sciences or a related discipline.
• Experience working within a research laboratory environment and familiarity with molecular and cellular biology techniques.

Aufgaben

• Perform laboratory techniques including primary cell culture, RT-qPCR, ELISA, western blotting and immunostaining.
• Support performing and monitoring animal models of pulmonary vascular disease.
• Generate, analyse and interpret experimental data and maintain accurate records.
• Contribute to day-to-day operation of the research laboratory.
• Participate in research group meetings and assist preparation of publications and reports.
• Collaborate with leading researchers in pulmonary vascular biology and complement biology.

Kenntnisse

Molecular biology

Cell culture

qPCR

ELISA

Western blotting

Immunostaining

Multidisciplinary teamwork

Ausbildung

BSc or MSc in Biological Sciences or related

Tools

Microscopy

Animal models

Jobbeschreibung

About the role

We are seeking a motivated Research Assistant to join a British Heart Foundation (BHF)-funded project investigating how the complement system contributes to pulmonary arterial hypertension. Based within the Vascular Sciences Section of the National Heart and Lung Institute at Imperial College London, you will work on an exciting translational research programme combining animal models, primary cell culture, molecular biology and omics approaches to understand disease mechanisms and identify new therapeutic opportunities for patients.

What you would be doing

• Perform a range of laboratory techniques including primary cell culture, RT-qPCR, ELISA, western blotting and immunostaining.
• Support performing and monitoring animal models of pulmonary vascular disease.
• Generate, analyse and interpret experimental data and maintain accurate research records.
• Contribute to the day-to-day operation of the research laboratory.
• Participate in research group meetings and assist the preparation of publications and reports.
• Work alongside leading researchers in pulmonary vascular biology, cardiovascular disease and complement biology.

What we are looking for

• A BSc or MSc in Biological Sciences, Biomedical Sciences or a related discipline.
• Experience working within a research laboratory environment.
• Experience of molecular and cellular biology techniques including cell culture and common laboratory assays such as qPCR, ELISA, western blotting and immunostaining.
• Knowledge of cardiovascular, vascular or inflammatory disease biology.
• Strong communication and organisational skills, and ability to work as part of a multidisciplinary team.

Desirable

• Experience with animal models of disease.
• Experience in cardiovascular biology or pulmonary vascular disease research.
• Knowledge of complement biology.
• Experience with microscopy.

What we can offer you

• Working on a British Heart Foundation-funded project with clear clinical relevance.
• Training in a broad range of in vivo and in vitro experimental techniques.
• Collaboration with internationally recognised experts in pulmonary hypertension and complement research.
• Opportunities to contribute to high-impact publications and scientific conferences.
• A collaborative and supportive research environment.

Further Information

This is a full-time post on a fixed-term contract for three years. This can start from January 2027 or later following necessary approvals e.g. visa status.

The successful candidate will join the Vascular Sciences Section within the National Heart and Lung Institute and work closely with Professor Allan Lawrie, Professor Martin Wilkins, Professor Matthew Pickering and collaborators across academia and industry.

If you require any further details about the role, please contact: Dr Merve Keles – [e-mail].

About Imperial

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.

Join us and be part of something bigger. From global health to climate change, AI to business leadership, we navigate some of the world’s toughest challenges. Whatever your role, your contribution will have a lasting impact.

As a member of our vibrant community of 22,000 students and 8,000 staff, you’ll collaborate with passionate minds across nine London campuses and a global network.

This is your chance to help shape the future. We hope you’ll join us at Imperial.

£45,399 to £48,876 per annum