Research Assistant

Imperial Enterprise; London Borough of Hammersmith and Fulham; On-site; GBP 45,000 - 49,000; Full time

Job summary

Imperial College London is seeking a Research Assistant in the Department of Immunology and Inflammation to explore hepatotoxicity mechanisms of an antibody-drug conjugate in leukaemia models. The role collaborates with senior researchers and involves advanced cell culture and sequencing techniques, on-site at Hammersmith Campus.

The candidate will bring biology training and hands-on lab experience, including flow cytometry and sequencing, with animal work desirable.

Qualifications

• First/masters degree (or equivalent) in Biology or related discipline.
• Experience in a laboratory research environment and conducting laboratory techniques, including multi-colour flow cytometry and sequencing methods.
• Prior animal work is desirable but not essential.

Responsibilities

• Work closely with a post-doctoral research associate and be trained in techniques.
• Endothelial cell culture, mini-liver culture models, flow cytometry.
• Single cell and bulk RNA sequencing and transgenic mouse models of leukaemia.

Skills

Flow cytometry

Endothelial cell culture

Cell culture techniques

RNA sequencing

Education

Biology degree (BSc/MSc)

Tools

Flow cytometer

Sequencing methods

Job description

Job number MED06035 Faculties Faculty of Medicine Departments Department of Immunology and Inflammation Salary or Salary range £45,399 - £48,876 per annum Location/campus Hammersmith Campus - On site only Contract type work pattern Full time - Fixed term Posting End Date 4 Nov 2026

About the role

We are looking for a talented Research Assistant to work on an exciting project exploring the underlying cause of the hepatotoxicity induced by an antibody drug conjugate Inotuzumab Ozogamicin, used to treat leukaemia. You will be working in Associate Professor Richard Burt’s laboratory, on a project exploring the hypothesis that Inotuzumab Ozogamicin causes hepatotoxicity through endothelial cell activation and damage. The post is funded by the Medical Research Foundation.

What you would be doing

You will work closely with a post-doctoral research associate and be trained in techniques including endothelial cell culture, ‘mini-liver’ culture models, flow cytometry, single cell and bulk RNA Sequencing and transgenic mouse models of leukaemia.

What we are looking for

You should have a first/masters degree (or equivalent) in Biology, or a related discipline. You should have experience of working in a laboratory research environment and conducting laboratory techniques, including multi colour flow cytometry and experience in sequencing methods. Prior experience of animal work is desirable, but not essential.

What we can offer you

• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
• Sector-leading salary and remuneration package (including 43 days off a year and generous pension schemes).
• Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing .

Further information

This is a full-time, fixed-term post until 15 July 2029, with potential for an extension to November 2029 dependent on funding.

If you have any further details about the role, please contact Dr Richard Burt ([e-mail]) or Dr Penny Sparkes ([e-mail]).

Attached documents are available under links. Clicking a document link will initialize its download.

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above.

We reserve the right to close the advert before the stated closing date, should we receive a high volume of applications. It is therefore advisable that you submit your application as early as possible to avoid disappointment.

If you encounter any technical issues while applying online, please don't hesitate to email us at [e-mail]. We're here to help.

About Imperial

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