Remote Senior Principal Statistician - Early Phase

Syneos Health, Inc.; Greater London; Hybrid; GBP 90,000 - 130,000; Full time

Job summary

Syneos Health in the United Kingdom is seeking a Sr/Principal Statistician (Sponsor-dedicated) for Early Phase projects, with remote work options across EMEA. The role involves statistical leadership across the drug development lifecycle from protocol to CSR, and collaboration with sponsor teams.

PhD or MS in statistics with at least 3 years pharmaceutical experience is required. Strong knowledge of advanced statistical methods and R for analyses; early-phase experience strongly preferred.

Qualifications

• PhD/MS in statistics or related discipline with at least 3 years of pharmaceutical experience.
• Good knowledge and understanding of advanced statistical concepts and methods.
• Able to do advanced statistical analyses using R.
• Experience with early-phase clinical trials strongly preferred.

Responsibilities

• Provides support across all assigned statistical tasks during the lifecycle of the project, from protocol to CSR.
• Prepares Statistical Analysis Plans (SAPs), including development of well-presented mock-up displays for tables, listings, and figures. Collaborate with the sponsor, if required.
• May be responsible for the statistical aspects of the protocol, generation of randomization schedule, publications and input to the clinical study report.
• Coordinates the activities of other biostatistics and statistical programming personnel on assigned projects to ensure timely completion of high quality work.
• Manages scheduling and time constraints across multiple projects, sets goals based on priorities from management, adapts to timeline or priority changes by reorganizing daily workload, and proactively communicates to biostatistics management any difficulties with meeting these timelines.
• May lead projects involving integrated analyses, attend regulatory agency meetings or respond to questions, as needed, to support the statistical analysis results of clinical trials on behalf of the sponsor.
• Follows applicable SOPs, WIs, and relevant regulatory guidelines (e.g. ICH).
• Maintains well organized, complete, and up-to-date project documentation, and verification/quality control documents and programs; ensuring inspection readiness.
• Minimal travel may be required.

Skills

Advanced statistical concepts

Clinical trial statistics

Education

PhD/MS in statistics or related discipline

Tools

R

Job description

Syneos Health in the United Kingdom is seeking a Sr/Principal Statistician (Sponsor-dedicated) for Early Phase projects, with remote work options across EMEA. The role involves statistical leadership across the drug development lifecycle from protocol to CSR, and collaboration with sponsor teams.

PhD or MS in statistics with at least 3 years pharmaceutical experience is required. Strong knowledge of advanced statistical methods and R for analyses; early-phase experience strongly preferred.