Proteomics & Structural Bioinformatics Architect

EMBL-EBI - European Bioinformatics Institute; Hinxton; On-site; GBP 60,000 - 90,000; Full time

Job summary

EMBL-EBI - European Bioinformatics Institute in Hinxton, United Kingdom, invites applications for a Bioinformatician specializing in structural biology, proteomics and integrative modelling. You will help connect XL-MS, CF-MS, AP-MS data with structural restraints and integrative models, building FAIR infrastructure and open data workflows.

You will work with PRIDE and wwPDB to establish deposition workflows, validation methods and shared access services, enabling reuse and interoperability of

Qualifications

• PhD in Bioinformatics or related field.
• Familiarity with structural biology and proteomics data.
• Experience with scientific software development (Python).
• Experience with data standards and reproducible research practices.

Responsibilities

• Analyse XL-MS, CF-MS, AP-MS and integrative modelling workflows to define data requirements.
• Extend and adopt community standards for structural interactomics data.
• Develop data models and interoperable software tools to connect proteomics and structural biology formats.
• Develop tools, APIs, workflows and documentation for standard-compliant data deposition and validation.
• Implement cross-modality validation and provenance tracking between evidence, restraints and models.
• Collaborate with PRIDE and PDB-IHM to establish deposition and access workflows.
• Contribute to integrated search, visualization and programmatic access services.
• Engage with researchers and standards communities to test and advance infrastructure.
• Contribute to publications, documentation and training materials.

Skills

Python

Git

Communication

Collaboration

Problem-solving

Education

PhD in Bioinformatics

Tools

Containerisation

REST APIs

Workflow-management systems

Docker

Job description

EMBL-EBI - European Bioinformatics Institute in Hinxton, United Kingdom, invites applications for a Bioinformatician specializing in structural biology, proteomics and integrative modelling. You will help connect XL-MS, CF-MS, AP-MS data with structural restraints and integrative models, building FAIR infrastructure and open data workflows.

You will work with PRIDE and wwPDB to establish deposition workflows, validation methods and shared access services, enabling reuse and interoperability of