Bioinformatician: Structural Interactomics Modeling

embl; Hinxton; On-site; GBP 60,000 - 90,000; Full time

Benefits offered by this job

Public transport discount

Job summary

European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, invites a Bioinformatician to join the Velankar team. The role focuses on connecting structural interactomics experiments with proteomics evidence and integrative models, contributing to standards and workflows across repositories.

You will develop practical representations for experimental context, extend community standards, and build data models and APIs to enable deposition, validation, and reuse of datasets.

Qualifications

• PhD in Bioinformatics, Computational Biology, Structural Biology, Proteomics, Computer Science or related field.
• Familiarity with structural biology, protein structure or molecular interaction data.
• Experience with biological data, metadata, identifiers and scientific repositories.
• Understanding of sequence, structure and functional annotations of proteins.
• Experience in scientific software development, preferably using Python.
• Experience designing data-integration workflows, APIs or data-processing pipelines.
• Familiarity with FAIR data principles, metadata standards and reproducible research practices.
• Experience with Linux environments, Git, testing and documentation practices.
• Scientific publications relevant to structural biology and proteomics.

Responsibilities

• Analyse current XL-MS, CF-MS, AP-MS and integrative modelling workflows to define data and metadata requirements.
• Contribute to the extension and adoption of community standards for structural interactomics and integrative modelling data.
• Develop data models and interoperable software tools that connect proteomics and structural biology formats, including suitable conversion of proteomics outputs into integrative modelling representations.
• Develop and maintain tools, APIs, workflows and documentation that support standard-compliant data deposition and local validation.
• Implement approaches for cross-modality validation, identifier mapping and provenance tracking between experimental evidence, structural restraints and integrative models.
• Work with PRIDE and PDB-IHM colleagues to establish linked deposition, release and access workflows across relevant resources.
• Contribute to integrated search, visualisation and programmatic access services for structural interactomics data.
• Engage with researchers, analysis-tool developers and standards communities to support testing, adoption and further development of the infrastructure.
• Contribute to scientific publications, technical documentation, training and dissemination activities.

Skills

Python

Linux environments

Git

Data integration

Documentation practices

Education

PhD in Bioinformatics, Computational Biology, Structural Biology, Proteomics, Computer Science or related field

Tools

PRIDE

Job description

European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, invites a Bioinformatician to join the Velankar team. The role focuses on connecting structural interactomics experiments with proteomics evidence and integrative models, contributing to standards and workflows across repositories.

You will develop practical representations for experimental context, extend community standards, and build data models and APIs to enable deposition, validation, and reuse of datasets.