Principal Scientist - High-Throughput Bioprocess Technology Development

Lonza, Inc.; Princes Risborough; On-site; Confidential; Full time

Job summary

Lonza is seeking a technically skilled Bioprocess Engineer to develop and deploy high-throughput technologies and scale-down models supporting biologics process development in the UK. The role focuses on identifying gaps, delivering automated, data-rich solutions, and leading DoE-driven concept studies.

You will collaborate with Cell Expression, Upstream/Downstream Processing, Analytics, Automation, and Digital teams, translating early-stage needs into scalable platforms while travelling to

Qualifications

• MSc/PhD in biochemical engineering, chemical engineering, bioengineering, bioprocess engineering, biotechnology or related discipline.
• Demonstrated experience in technology development relevant to bioprocessing (miniaturized systems, microfluidics, process sensing, fluidics, high-throughput experiments).
• Experience with structured experimental design (DoE) and data-driven technology development.

Responsibilities

• Develop and deploy high-throughput technologies and scale-down models to support upstream and downstream biologics process development.
• Identify technology gaps and deliver innovative bioprocess engineering solutions that enhance process control, monitoring, automation and data capture for sensors, fluidics and automation.
• Design and lead proof-of-concept studies to evaluate feasibility, robustness and scalability of emerging bioprocess technologies.
• Establish standardised approaches and best practices for model setup, automation, sampling and performance assessment.
• Partner across Cell Expression, Upstream/Downstream Processing, Analytical Development, Automation, Digital, Data Science and PAT to integrate new technologies into R&D capabilities.
• Scout, assess and introduce emerging technologies in high-throughput bioprocessing, miniaturisation, process sensing and automated sampling.
• Strong written and verbal communication skills, business-fluent English and willingness to travel between Lonza sites and external technology partners.

Skills

Problem-solving

Communication skills

Team collaboration

DoE / Data analysis

Education

MSc/PhD in biochemical engineering or related discipline

Tools

Miniaturized systems

Microfluidics

Process sensing

Fluidics

Automated experimental systems

Job description

global benefits can be also found on .

Key responsibilities:

• Develop and deploy high-throughput technologies and scale-down models to support upstream and downstream biologics process development.
• Identify technology gaps and deliver innovative bioprocess engineering solutions that enhance process control, monitoring, automation and data technical requirements for sensors, fluidics, automation, control strategies and experimental platforms, working with internal teams and external technology partners.
• Design and lead proof-of-concept studies to evaluate the feasibility, robustness, scalability and value of emerging bioprocess technologies.
• Establish standardised approaches and best practices for model setup, automation, sampling, data capture and performance assessment.
• Partner across Cell Expression, Upstream Processing, Downstream Processing, Analytical Development, Automation, Digital, Data Science and PAT to integrate new technologies into R&D capabilities.
• Scout, assess and introduce emerging
• technologies in high-throughput bioprocessing, miniaturisation, process sensing, microfluidics, automated sampling and advanced experimental requirements.
• MSc/PhD in biochemical engineering, chemical engineering, bioengineering, bioprocess engineering, biotechnology or related discipline.
• Demonstrated experience in technology development relevant to bioprocessing, such as miniaturized systems, microfluidics, process sensing, fluidics, analytical technologies or high-throughput experimental understanding of biologics process-development principles and critical process parameters, with the ability to translate process-development needs into technical requirements for new platforms and workflows.
• Ability to assess external technologies and partners, define proof-of-concept studies and translate successful solutions into reusable internal capabilities.
• Experience with structured experimental design, including DoE, statistical analysis or data-driven technology development.
• Strong scientific judgement, problem-solving and experimental-design capability, with the ability to lead complex technical projects across R&D, Operations and external partners.
• Experience developing, evaluating or implementing automated experimental systems, including sensors, liquid handling, sampling, control strategies or data-rich laboratory workflows is a plus.
• Strong written and verbal communication skills, business-fluent English and willingness to travel between Lonza sites and external technology partners as required

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone's ideas, big or small, have the potential to improve millions of lives, and that's the kind of work we want you to be part of.Innovation thrives when people