Principal Clinical Scientist

Alignerr Corp.; Oxford; Remote; GBP 83,000 - 165,000; Part time

Benefits offered by this job

Fully remote

Flexible hours

Contract extension potential

Job summary

Alignerr is seeking a Principal Clinical Scientist to shape AI training with rigorous clinical trials and regulator-ready data. This fully remote hourly contract role demands senior expertise in designing trial protocols and interpreting data for FDA/ EMA submissions, ensuring AI models meet high scientific standards.

You’ll work asynchronously across disciplines, providing expert feedback to improve how AI reasons about clinical evidence while maintaining regulatory discipline and scientific

Qualifications

• Senior-level experience designing clinical trial protocols for regulatory submission.
• Experience interpreting clinical data for agencies such as the FDA/EMA or equivalent.
• Strong grounding in biostatistics or translational science.
• Rigorous mindset with AI-generated outputs; high standards for evidence.
• Clear, precise written communication; ability to provide actionable feedback.
• Self-directed and reliable when working independently.

Responsibilities

• Design and review clinical trial protocols used to generate regulator-ready datasets for AI training.
• Interpret and audit clinical trial results to ensure accuracy and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment.
• Identify gaps and weaknesses in how AI reasons about clinical data and outcomes.
• Provide structured feedback to improve AI understanding of clinical evidence.
• Work independently and asynchronously on your own schedule.

Skills

Clinical trial design

Regulatory submissions

Data interpretation

Biostatistics

Regulatory science

Scientific communication

Independent work

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your career designing rigorous clinical trials and interpreting regulatory-grade data could directly shape how AI reasons about biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the development of cutting‑edge AI systems — ensuring the models influencing the future of medicine are built on a foundation of scientific rigor.

This is a fully remote, flexible contract role. You'll work at the intersection of clinical research and frontier AI, applying the same standards you'd bring to an FDA or EMA submission to train and evaluate the next generation of AI models.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations
• Identify gaps, errors, and weaknesses in how AI systems reason about clinical data and outcomes
• Provide structured, expert feedback that directly improves how AI understands clinical evidence
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous — you hold AI‑generated outputs to the same standards as real‑world submissions
• Clear and precise written communicator who can translate complex clinical reasoning into actionable feedback
• Self-directed and reliable when working independently

Nice to Have

• Prior experience with data annotation, data quality review, or AI evaluation systems
• Background in pharmacovigilance, clinical operations, or medical writing
• Familiarity with AI tools or content evaluation workflows as an end user
• Experience working across therapeutic areas or with cross‑functional research teams

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real‑world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-impact work
• Collaborate with leading AI research teams and labs on problems that matter
• Potential for ongoing work and contract extension as new projects launch