Principal Clinical Scientist

Alignerr Corp.; Greater London; Remote; GBP 83,000 - 165,000; Full time

Job summary

Alignerr is seeking a Principal Clinical Scientist to guide AI training with clinical trial expertise, ensuring regulator-ready data for real-world medical evidence. This fully remote, flexible hourly contract role invites senior scientists to shape how AI models interpret endpoints and outcomes, bridging clinical and technical teams.

You will design protocols, audit results, and ensure regulatory relevance across FDA/EMA expectations, with autonomy and ongoing project opportunities.

Qualifications

• Senior clinical scientist with hands-on trial design for regulatory submission.
• Experience interpreting data for FDA/EMA and regulatory agencies.
• Strong biostatistics and research methodology background.
• Ability to work independently in asynchronous remote setting.

Responsibilities

• Design and review trial protocols for regulator-ready AI datasets.
• Interpret and audit trial results for accuracy and regulatory relevance.
• Evaluate AI-generated analyses for scientific soundness.
• Provide expert feedback shaping AI models' handling of trial data.
• Help establish scientific standards for real-world evidence.

Skills

Clinical trial design

Regulatory submissions

Biostatistics

Regulatory compliance

Remote work

Tools

AI tools

Job description

Principal Clinical Scientist (AI Training)

What if your years of clinical trial expertise could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows — ensuring the clinical data that trains and evaluates next-generation AI systems meets the standards expected in real regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the cutting edge of biomedical AI without leaving their domain behind.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert feedback that directly shapes how AI models reason about clinical trial data, endpoints, and outcomes
• Help establish the scientific standards that frontier AI systems use to understand real-world clinical evidence

Who You Are

• Senior clinical scientist with deep, hands-on experience designing clinical trial protocols for regulatory submission
• Expert in interpreting clinical data for major regulatory agencies — FDA, EMA, or equivalent
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Detail-oriented and systematic — you hold data to a high standard and can articulate exactly why
• Comfortable working independently in an asynchronous, remote environment

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems
• Familiarity with AI tools or clinical informatics platforms
• Background in drug development, medical devices, or digital health research
• Experience bridging clinical and technical teams across complex research workflows

Why Join Us

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Influence how AI understands, evaluates, and communicates real-world clinical evidence at scale
• Fully remote and flexible — work on your own schedule, from anywhere
• Freelance autonomy with meaningful, expert-level work that matches your seniority
• Collaborate with leading AI research labs and teams on genuinely novel problems
• Potential for ongoing work and contract extension as projects evolve