Principal Analytical Scientist

Singular: Building Brilliant Biotechs; Chapel-en-le-Frith; On-site; GBP 70,000 - 100,000; Full time

Job summary

Singular: Building Brilliant Biotechs in the United Kingdom is seeking a Principal Analytical Scientist to lead cross‑program analytical development across multiple client projects within a CRO/CDMO environment. This senior role combines hands‑on science with technical leadership and strategic influence on analytical capabilities.

You will own analytical CMC activities from development through to clinical manufacture, mentor scientists, interact with clients, and help shape scientific strategy

Qualifications

• PhD or significant industrial experience in Analytical Chemistry.
• Strong expertise in chromatography and analytical method development.
• Project leadership experience.

Responsibilities

• Lead complex analytical development programmes across multiple client projects.
• Lead analytical CMC activities from development through to clinical manufacture.
• Act as a senior technical contact for external clients.
• Mentor and develop junior scientists.
• Contribute to scientific strategy, capability development and continuous improvement initiatives.

Skills

Analytical Chemistry

Chromatography

Analytical Method Development

Project Leadership

Education

PhD in Analytical Chemistry

Job description

You are an experienced analytical scientist with deep expertise in chromatography and analytical method development.

You want to work in a senior, highly visible role where you can influence analytical strategy, remain close to the science and help shape the development of analytical capabilities across multiple pharmaceutical and biotechnology programmes.

We are supporting the search for a Principal Analytical Scientist to join a growing analytical development group. This position combines hands-on science, technical leadership, client interaction and project ownership within a commercially focused CRO/CDMO environment.

This is an opportunity to take responsibility for analytical CMC activities from early development through to clinical manufacture, while helping clients navigate complex scientific and regulatory challenges. Given the current successes within this company there is significant scope for progression into more senior leadership positions.

THE ROLE

• Lead complex analytical development programmes across multiple client projects
• Lead analytical CMC activities from development through to clinical manufacture
• Act as a senior technical contact for external clients
• Mentor and develop junior scientists
• Contribute to scientific strategy, capability development and continuous improvement initiatives

ABOUT YOU

You will likely bring:

• PhD or significant industrial experience in Analytical Chemistry or a related scientific discipline
• Strong expertise in chromatography and analytical method development
• Project leadership experience

Additional "nice to have" experience:

• Exposure to PROTACs or other emerging modalities advantageous

Logistics

• 5 days' week onsite

If you're an accomplished analytical scientist looking for an opportunity to combine scientific excellence, client impact and technical leadership, we'd love to hear from you.