Principal Scientist

Nexus Life Sciences; Belfast City District; On-site; GBP 54,000 - 66,000; Full time

Benefits offered by this job

Competitive salary up to £60,000

Leadership role in a dynamic team

Exposure to regulatory submissions and

Audits and compliance

Collaborative and innovation-focused

Job summary

Nexus Life Sciences is seeking a Principal Scientist to lead our Clinical Method Development and Validation team. You will oversee bioanalytical method delivery for our New Product Development programme, providing technical leadership and ensuring continuous improvement in a GLP-compliant environment.

Advance HPLC/UPLC/LCMS/MS method development, optimise chromatographic systems for low-level analytes, and mentor the Method Development and Validation group in a collaborative, innovation-driven

Qualifications

• Degree in Biochemistry, Biomedical Science, or a related field.
• 4+ years' lab experience in a GxP environment, 2+ years in a managerial role.
• Expertise in HPLC, UPLC, LCMS/MS, and chromatography data systems.
• Strong technical, problem-solving, and time management skills.

Responsibilities

• Act as the expert in method development and analytical extraction techniques (e.g., protein precipitation, SPE, Liquid-Liquid).
• Optimise analytical systems (HPLC, UPLC, LCMSMS) and chromatographic methods for low-level analytes.
• Manage and mentor the Method Development and Validation team.
• Oversee bioanalytical method development and validation in compliance with GLP and international regulations.

Skills

HPLC

UPLC

LCMS/MS

Chromatography data systems

Leadership

Education

Biochemistry / Biomedical Science degree

Job description

Job Advertisement: Principal Scientist

Salary: Up to £60,000

Overview

We are looking for a highly skilled Principal Scientist to lead our Clinical Method Development and Validation team.

This role involves overseeing bioanalytical method delivery for our New Product Development programme, providing technical leadership, and ensuring continuous improvement in a GLP-compliant environment.

Responsibilities

• Act as the expert in method development and analytical extraction techniques (e.g., protein precipitation, SPE, Liquid-Liquid).
• Optimise analytical systems (HPLC, UPLC, LCMSMS) and chromatographic methods for low-level analytes.
• Manage and mentor the Method Development and Validation team.
• Oversee bioanalytical method development and validation in compliance with GLP and international regulations.

Qualifications

• Degree in Biochemistry, Biomedical Science, or a related field.
• 4+ years' lab experience in a GxP environment, 2+ years in a managerial role.
• Expertise in HPLC, UPLC, LCMSMS, and chromatography data systems.
• Strong technical, problem-solving, and time management skills.

Benefits

• Competitive salary up to £60,000.
• Leadership role in a dynamic team tackling cutting-edge research.
• Professional growth through exposure to regulatory submissions and audits.
• Collaborative and innovation-focused workplace.