Postdoctoral Researcher: Protein Engineering & RBC Interactions

1000scholars; West of England; On-site; GBP 45,000 - 50,000; Full time

Job summary

The University of Bristol is seeking a Postdoctoral Research Associate to join Professor Ashley Toye's group in the School of Biochemistry. This full-time fixed-term role (35 hours per week) is funded by Dstl and runs until 31 March 2027.

You will design, produce and characterise recombinant proteins, assess their interactions with red blood cells, and use flow cytometry and microfluidic flow systems across collaborations in protein engineering and biochemistry.

Qualifications

• PhD in biochemistry, molecular biology, protein engineering, synthetic biology or related discipline.
• Experience with recombinant DNA methods, bacterial protein expression and protein purification.
• Ability to design experiments and interpret quantitative results.

Responsibilities

• Design, produce and characterize recombinant proteins and investigate their interactions with red blood cells.
• Plan and troubleshoot experiments and analyse quantitative data.
• Maintain accurate records and contribute to meetings and final report.

Skills

Recombinant DNA methods

Bacterial protein expression

Protein purification

Flow cytometry

Mammalian expression

Enzyme assays

Microfluidics

Computational protein design

Education

PhD in biochemistry, molecular biology, protein engineering, synthetic biology or related discipline

Tools

Molecular cloning

Affinity chromatography

Size-exclusion chromatography

Microfluidic systems

Biochemical activity assays

Mammalian expression

Job description

The University of Bristol is seeking a Postdoctoral Research Associate to join Professor Ashley Toye's group in the School of Biochemistry. This full-time fixed-term role (35 hours per week) is funded by Dstl and runs until 31 March 2027.

You will design, produce and characterise recombinant proteins, assess their interactions with red blood cells, and use flow cytometry and microfluidic flow systems across collaborations in protein engineering and biochemistry.