Postdoctoral Researcher - Genome Integrity

1000scholars

Dundee

Hybrid

GBP 38,000 - 46,000

Full time

5 days ago
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Job summary

University of Dundee in Dundee, United Kingdom, is seeking a Postdoctoral Researcher - Genome Integrity funded by Cancer Research UK, with a salary of GBP 37,694 - 46,049 per year. The role focuses on cell enlargement, senescence, and genome instability in cancer progression and treatment.

You will apply omics, live-cell microscopy, and CRISPR screens to identify vulnerabilities in enlarged cells. Ideal candidates hold a PhD with at least one first author publication and a strong background in

Qualifications

  • PhD in a relevant scientific area with at least one first author publication.
  • Strong background in cell biology and experience in the senescence field.
  • Experience with omics approaches and modern cell biology techniques.

Responsibilities

  • Use various omics approaches to study how cell enlargement drives senescence after cancer therapy.
  • Use live-cell microscopy to characterize the transition into senescence.
  • Study how cell enlargement leads to genome instability after senescence evasion.
  • Perform CRISPR screens to identify vulnerabilities in enlarged mammalian cells.

Skills

Cell biology
Senescence
Omics approaches
Live-cell microscopy
Cancer biology

Education

PhD in relevant scientific area

Tools

CRISPR screens
Live-cell microscopy
Genomics analyses

Job description

# Postdoctoral Researcher - Genome IntegrityUniversity of DundeeDundee, United KingdomPostdoctoralMolecular BiologyCell BiologyMicroscopyNo deadline given## About the positionPostdoctoral Researcher - Genome Integrity University of Dundee Dundee, United Kingdom GBP 37,694 - 46,049 per year We are looking for a talented ambitious postdoctoral researcher to join a Cancer Research UK-funded programme to examine the role of cell enlargement and senescence in cancer progression and treatment. This builds on our recent work demonstrating a role for cell enlargement in driving senescence and genome instability following anti-cancer therapy. Your priorities will include: Using various 'omics approaches to examine how cell enlargement drives senescence following cancer therapy. Using a wide range of cell biology methods, including live-cell microscopy, to characterise the transition into senescence. Studying how cell enlargement drives genome instability following senescence evasion or escape. Performing CRISPR screens to identify targetable vulnerabilities in enlarged mammalian cell types. Who we are looking for: A highly-motivated and ambitious postdoctoral researcher with a passion for science. A candidate with a PhD in relevant scientific area, with at least one main author publication. A candidate with a strong scientific background in cell biology and experience of working in the senescence field. Apply Now Deadline 11 November Don't forget to mention EuroScienceJobs when applying.
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