Postdoctoral Research Scientist - Mechanistic Modelling for Rare Disease Digital Twins

NBI Partnership; Norwich; Hybrid; GBP 39.000 - 47.000; Vollzeit

Zusammenfassung

Earlham Institute in Norwich invites applications for a Postdoctoral Research Scientist in Mechanistic Modelling for Rare Disease Digital Twins. The role focuses on developing executable models and reusable Digital Twins to advance understanding of rare diseases within the Chan Zuckerberg Initiative-funded Digital Twin program.

You will adapt models from BioModels and Reactome, build de-novo networks, and parameterise and validate models against literature and data.

Aufgaben

• Conduct primary research to develop executable mechanistic models and reusable Digital Twins for rare diseases.

Jobbeschreibung

Postdoctoral Research Scientist - Mechanistic Modelling for Rare Disease Digital Twins

Job Title Postdoctoral Research Scientist - Mechanistic Modelling for Rare Disease Digital Twins Post Number 1006212 Closing Date 6 Dec 2026 Grade SC6 Starting Salary Salary: £39,000-£46,500

Hours per week 37 Project Title Development of Digital Twins for modelling rare diseases and exploring potential applications Months Duration 24

Job Description

Main Purpose of the Job

The post holder will conduct primary research in the Sheriff Group to develop executable mechanistic models and reusable Digital Twins for rare diseases within the Chan Zukerberg Initiative-funded Digital Twin program.
The role will focus on adapting curated models and pathways from BioModels, Reactome and the literature; constructing de-novo mechanistic models from disease- and phenotype-specific networks; parameterising and validating models using