Senior Computational Biologist - AI-Driven Digital Twins

Earlham Institute

Norwich

Hybrid

GBP 47,000 - 58,000

Full time

9 hours ago

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Job summary

The Earlham Institute in Norwich is seeking a Senior Computational Biologist to lead AI-enabled Digital Twins for rare diseases. The role blends bioinformatics, multi-omics analysis, and practical AI/ML with systems modelling to build reusable Digital Twin models and validate them through cross-disciplinary collaboration.

You will lead data integration, develop hybrid AI and mechanistic approaches, and drive open workflows while mentoring junior colleagues.

Qualifications

PhD awarded or expected within 6 months in Computational Biology or related field.
Demonstrated motivation and alignment with rare-disease Digital Twin aims.
Evidence of independence and leadership of substantial outputs/workstreams.

Responsibilities

Process, harmonise, analyse and integrate multi-omics data for Digital Twins.
Lead a defined integration workstream with milestones and risk management.
Develop hybrid mechanistic-AI modelling approaches for end-to-end Digital Twins.
Apply Digital Twins to rare-disease questions and patient stratification.
Prepare manuscripts and contribute to open dissemination of models and workflows.