Postdoctoral Scientist

University of Oxford; Oxford; On-site; GBP 40,000 - 52,000; Full time

Job summary

The University of Oxford, within the Big Data Institute (BDI) and the Institute of Developmental & Regenerative Medicine (IDRM), invites applications for a Postdoctoral Scientist to lead research on biomarkers and disease mechanisms in RNUopathies and ReNU syndrome. You will drive genomic and transcriptomic analysis in human samples, cell lines, and mouse models to advance therapeutic development.

You will supervise MSc and PhD students, ensure robust data quality and documentation, disseminate

Responsibilities

• Lead bioinformatic and statistical analysis of large-scale genomic and transcriptomic datasets.
• Develop and implement novel analytical approaches for snRNA-related research.
• Lead the research project and collaborate with internal and external researchers.
• Supervise MSc and PhD students and ensure data quality and documentation.
• Disseminate findings via publications, presentations and conferences.
• Engage with patient advocacy groups and support public outreach.

Job description

We are seeking a Postdoctoral Scientist to lead cutting-edge research into biomarkers and disease mechanisms to enhance therapeutic development for RNUopathies, including ReNU syndrome. Based within the Big Data Institute (BDI) and the Institute of Developmental & Regenerative Medicine (IDRM), you will join a multidisciplinary team investigating therapeutic approaches for rare neurodevelopmental disorders caused by variants in small nuclear RNA (snRNA) genes.

You will lead bioinformatic and statistical analysis of large-scale genomic and transcriptomic datasets from human samples, cell lines, and mouse models; developing and implementing novel analytical approaches where appropriate; leading the research project; collaborating with internal and external researchers; contributing to the supervision of MSc and PhD students; maintaining high standards of data quality, integrity, and documentation; disseminating findings through publications, presentations, and conferences; engaging with patient advocacy groups; and supporting public engagement and outreach activities. This is an exciting opportunity to contribute to pioneering rare disease research within a highly collaborative environment and to develop your own scientific profile within a world-leading therapeutic genomics programme.