Postdoc: Native Mass Spectrometry for SLC Transporters

University of Oxford; Oxford; On-site; GBP 43,000 - 48,000; Full time

Benefits offered by this job

Contributory pension

38 days annual leave

Childcare services

Family leave schemes

Cycle loan

Social clubs membership

Discounted travel

Job summary

The University of Oxford’s Department of Biochemistry invites applications for a full-time, fixed-term post leading the group’s native mass spectrometry research within the Kavli Institute for Nanoscience. The post holder will work on SLC transporter biology in mammalian cells.

You should hold a PhD in a related field with extensive experience in native top-down MS on high‑resolution Orbitrap instruments, expertise in sample prep and data analysis (preferably Python), and a strong publication

Qualifications

• PhD/ DPhil in biophysical chemistry or related field.
• Experience with native top-down MS on high‑resolution Orbitrap platforms.
• Expertise in sample preparation, fragmentation techniques, and protein modification analysis.
• Experience in proteomics, lipidomics and membrane protein expression/purification.

Responsibilities

• Lead the group’s native MS research within the project.
• Contribute to studies on how SLC transporters are folded, modified, trafficked and regulated in mammalian cells.
• Collaborate with PI and senior researchers; publish findings.
• Develop and apply computational/data-analysis tools (Python) as part of the project.

Skills

Mass spectrometry

Orbitrap UHMR

Top-down MS

Sample prep

Proteomics

Lipidomics

Python

Membrane proteins

SLC transporters

Data analysis

Education

PhD in Biophysical Chemistry

Tools

Python tools

Mass spectrometry software

Job description

The University of Oxford’s Department of Biochemistry invites applications for a full-time, fixed-term post leading the group’s native mass spectrometry research within the Kavli Institute for Nanoscience. The post holder will work on SLC transporter biology in mammalian cells.

You should hold a PhD in a related field with extensive experience in native top-down MS on high‑resolution Orbitrap instruments, expertise in sample prep and data analysis (preferably Python), and a strong publication