Postdoc: Gene Regulation & High-Throughput CRISPR

UKRI International; Greater London; Hybrid; GBP 43,000 - 60,000; Full time

Job summary

MRC Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR screens is based in the Genomic Variation and Disease Group (LMS 2880) in London. The role focuses on exploring how genomic variation influences disease using CRISPR/Cas9 editing and high-throughput screens, with opportunities for publication and grant submissions.

The successful candidate will join a collaborative team, contribute to data analysis and interpretation, and participate in training and development

Qualifications

• PhD (or equivalent) in Molecular Genetics or a closely related discipline.
• Background in gene regulation and/or developmental genetics.
• Experience with CRISPR/Cas9 genome editing and high-throughput CRISPR screens.
• Excellent written English and ability to write clearly for publication.

Responsibilities

• Design experiments, analyse data, visualize results and interpret findings.
• Prepare work for publication and grant submissions.
• Present at seminars and conferences as required.
• Contribute to running the laboratories with staff and students.
• Assist in supervision of undergraduate and postgraduate researchers.

Skills

Gene regulation

Developmental genetics

Mouse ES cell culture

CRISPR/Cas9 genome editing

High-throughput CRISPR screens

NGS library prep

Immunofluorescence

Microscopy

Single-cell analysis

cHi-C

ATAC-seq / Cut&Tag

English scientific writing

Education

PhD in Molecular Genetics or related

Tools

NGS library prep

Immunofluorescence

Microscopy

Single-cell analysis tools

ChIP-seq / Cut&Tag

Job description

MRC Postdoctoral Research Scientist in Gene Regulation and High-Throughput CRISPR screens is based in the Genomic Variation and Disease Group (LMS 2880) in London. The role focuses on exploring how genomic variation influences disease using CRISPR/Cas9 editing and high-throughput screens, with opportunities for publication and grant submissions.

The successful candidate will join a collaborative team, contribute to data analysis and interpretation, and participate in training and development