PET QC Chemist

Calyx; Greater London; On-site; GBP 35,000 - 52,000; Full time

Benefits offered by this job

25 days holiday

Private healthcare

Dental insurance (optional)

Cycle to Work scheme

Company Pension Scheme (matching up to

Job summary

Calyx in the United Kingdom is seeking a QC Scientist to perform method development and routine analysis of PET radiotracers in a GMP environment. You will drive QC of radiotracers, validate methods, document results and support clinical and pre-clinical studies.

Experience with HPLC and cGMP, plus data processing (HPLC/GC), is essential; knowledge of short-lived isotopes (e.g., carbon-11, fluorine-18) is advantageous.

Qualifications

• Minimum 2 years in a QC laboratory.
• Experience in HPLC.
• Experience in aGMP environment.
• Bachelor’s degree in Chemistry or related field.

Responsibilities

• QC of radiotracers according to project distribution and scanning schedule.
• Method development, validation and documentation for new radiotracers.
• Provide routine QC support to clinical and pre-clinical studies.
• Analytical chemistry support for precursor characterization and purification.
• Data processing including HPLC and GC.
• Document QC records to ensure cGMP compliance.
• Investigate OOS results and deviations within QMS.
• Present QC issues during audits if required.
• Train others in your area of expertise.
• Keep up to date with procedures, policies and new analytical techniques.

Skills

QC laboratory

HPLC

GMP

Education

BSc in Chemistry or related

Tools

GC

Job description

What can we offer you?

Apart from job satisfaction, we can offer you:

YOURSELF

• 25 days’ holiday (with the option to buy more)

HEALTH

• Private Healthcare

• Optional dental insurance, health assessments and health cash plans

• Cycle to Work scheme

WEALTH

• Company Pension Scheme, matching contributions up to 5% of salary

• Life assurance

• Annual staff bonus scheme

• Season ticket loans

Job Summary

In this role you’ll perform QC method development and routine analysis of PET radiotracers to support clinical and pre-clinical studies in a GMP environment.

Job Responsibilities

• QC of assigned radiotracers according to project distribution and the scanning schedule.

• QC implementation of newly assigned radiotracers: method development, validation and documentation.

• Providing routine QC support to clinical and pre-clinical studies.

• Providing analytical chemistry support for precursor characterization, radiotracer and radioligand purification.

• Data processing including HPLC and GC.

• Documenting QC records to ensure compliance with cGMP.

• Raising and investigating Out Of Specification (OOS) results and Deviation within QMS.

• Presenting technical QC issues to internal and external audits, if required.

• Training and educating others in your area of expertise.

• Keeping up to date with relevant procedures and policies, as well as new analytical techniques and processes (small molecules and biological products).

• Presenting results to internal and external audiences, when required.

• Maintaining adequate stocks of laboratory supplies

• Completing routine laboratory tasks, e.g., preparing HPLC buffers, calibration standards, etc.

Required Skills:

• Minimum 2 years’ experience in a QC laboratory.

• Experience in HPLC

• Experience in aGMP environment

Knowledge and Preferred Skills:

• Experience in GC is an advantage.

• Experience working with short-lived radioisotopes preferable (especially carbon-11 and fluorine-18) is desirable.

• Experience in change control is preferable.

Education:

• Undergraduate degree in Chemistry or a related scientific discipline