Manufacturing Science & Technology (MSAT) Team Member

Dr. Reddy's Laboratories; Lower Hopton; On-site; GBP 60,000 - 90,000; Full time

Benefits offered by this job

Defined contribution pension scheme

Life assurance

Private health insurance for self and…

Sickness Absence

Income Protection Scheme

Travel Insurance- Business andPersonal

Sports and Health club membership fee?

Cycle to work scheme

Enhanced Maternity / Paternity leave

Job summary

Dr. Reddy's Laboratories in Mirfield (West Yorkshire) seeks an MSAT team member to bridge development and commercial API manufacturing. You will lead tech transfers, drive CPI, and ensure robust processes under a cGMP framework, delivering scalable, compliant production of active ingredients.

The role covers technology transfer, validation support, deviation handling, and lifecycle management with significant cross-functional collaboration across QA, regulatory, and manufacturing teams.

Qualifications

• Bachelor’s, Master’s, or Ph.D. in Chemical Engineering, Chemistry, Pharmaceutical Sciences, or a closely related technical discipline
• Minimum 5 Years of experience in pharmaceutical industry

Responsibilities

• Technology Transfer & Scale-Up: support transfer of API/intermediate processes to commercial-scale manufacturing.
• Conduct feasibility studies and optimization experiments in labs.
• Perform facility-fit assessments, mass/energy balances, and scale-up modeling.
• Draft, review, and execute Technology Transfer Protocols and risk assessments (FMEA).
• Support EHS with analysis and interpretation of process safety data.
• Process Validation & Monitoring: assist Validation plans and CPV per ICH guidelines.
• Provide real-time shop floor technical support during campaigns and validation batches.
• Deviation and CAPA: act as SME for deviations and use RCA tools to implement corrective actions.
• Continuous Improvement & Lifecycle Management: identify process optimization and lifecycle change effects.
• Regulatory & Compliance Support: assist regulatory filings and participate in inspections.

Skills

Root-cause analysis

CAPA management

Process optimization

Cross-functional collaboration

cGMP/compliance

Education

Chemical Engineering / Chemistry / Pharmaceutical Sciences (BSc/MSc/PhD)

Job description

Company Description

Dr. Reddy's Laboratories Ltd. is an integrated global pharmaceutical company committed to providing affordable and innovative medicines for healthier lives. We have a commercial presence in more than 40 countries and 23,000 employees worldwide are part of our success. Our purpose is to accelerate access to affordable medicines because we believe Good Health Can’t Wait.

Situated in the heart of West Yorkshire, our Active Pharmaceutical Ingredient (API) manufacturing site in Mirfield, is part of Dr. Reddy’s global network of API and formulation manufacturing sites. Our Mirfield team specializes in producing complex APIs in accordance with the quality standards of the MHRA and international regulatory authorities. We also make intermediates and activated mPEGs which make us independent from global supplies. Today, we have produced pharmaceutical ingredients for more than three decades (since 1986).

Job Description

We are looking for MSAT team member who will serve as the technical bridge between process development and commercial production. Operating within a cGMP environment, this role provides end-to-end technical oversight, process engineering expertise, and scientific support to ensure the robust, scalable, and safe manufacture of Active Pharmaceutical Ingredients (APIs). The successful candidate will drive technology transfers, lead complex root‑cause investigations, and champion continuous process improvement (CPI) to optimise product yield and quality.

Responsibilities

1. Technology Transfer & Scale-Up

• Support the technical transfer of new API / Intermediate chemical synthesis processes from MSAT lab or external customers into commercial-scale manufacturing.
• Conduct laboratory experiments for feasibility studies and / or continuous improvement purpose.
• Perform facility-fit assessments, chemical engineering calculations (e.g., mass/energy balances, heat transfer, mixing dynamics), and scale-up modeling.
• Draft, review, and execute Technology Transfer Protocols, Campaign Summary Reports, and regular technical risk assessments (FMEA).
• Support to the EHS department in analysis the process safety data and interpretation.

2. Process Validation & Monitoring

• Support to the Validation program Process / clean protocols and Continued Process Verification (CPV) plans in alignment with ICH guidelines and Quality compliance requirements.
• Provide real-time shop floor technical support during active manufacturing campaigns and validation batches.

3. Deviation, Investigation & CAPA Management

• Act as the Technical Subject Matter Expert (SME) for manufacturing deviations, batch failures, and out-of-specification (OOS) results.
• Utilise structured root-cause analysis (RCA) tools (e.g., Fishbone, 5 Whys) to determine technical root causes and implement robust Corrective and Preventive Actions (CAPAs).

4. Continuous Improvement & Lifecycle Management

• Identify and implement process optimisation initiatives to enhance yield, minimise impurity profiles, reduce solvent consumption, and cut cycle times.
• Manage technical aspects of lifecycle changes, authoring technical justifications for change controls.

5. Regulatory & Compliance Support

• Support the technical queries for regulatory filing queries.
• Participate as a technical SME during regulatory inspections and client audits.

Qualifications

Education

Bachelor’s, Master’s, or Ph.D. in Chemical Engineering, Chemistry, Pharmaceutical Sciences, or a closely related technical discipline

Experience

Minimum5 Years of experience in pharmaceutical industry.

Benefits

We offer competitive salary and comprehensive benefits like

• Defined contribution pension scheme
• Life assurance
• Private health insurance for self and family
• Sickness Absence
• Income Protection Scheme
• Travel Insurance- Business and Personal
• Sports and Health club membership fee reimbursement
• Cycle to work scheme
• Enhanced Maternity / Paternity leave

Our Work Culture

Ask any employee at Dr. Reddy’s why they come to work every day and they’ll say, because Good Health Can’t Wait. This is our credo as well as the guiding principle behind all our actions. We see healthcare solutions not only as scientific formulations, but as a means to help patients lead healthier lives, and we’re always attuned to the new and the next to empower people to stay fit. And to do this, we foster a culture of empathy and dynamism. People are at the core of our journey over the last few decades. They have been supported by an enabling environment that buoys individual ability while fostering teamwork and shared success. We believe that when people with diverse skills are bound together by a common purpose and value system, they can make magic.