iPSC Neuroscience Technician for FA Research – Flexible

The University of Sheffield; Sheffield; On-site; GBP 32,000 - 37,000; Full time

Benefits offered by this job

38 days annual leave (pro rata)

Flexible working (hybrid)

Generous pension scheme

Discounts and rewards on shopping/eat

Staff networks

Job summary

The University of Sheffield seeks a Research Technician to support SITraN’s Friedreich’s ataxia project. You will maintain iPSC cultures, generate iPSC-derived neurons, and support cellular/molecular studies including ICC, fluorescence microscopy and RNA-seq sample prep.

The role involves data collection, record-keeping and teamwork across a multidisciplinary neuroscience lab, with opportunities to develop technical expertise.

Qualifications

• Minimum MSc in Neuroscience or related subject or Honours in Neuroscience or related field.
• Demonstrable experience with induced pluripotent stem cell (iPSC) models.
• Experience working in a collaborative research environment.
• Experience maintaining iPSC cultures and deriving iPSC neurons.
• Desirable: ICC, fluorescence microscopy, RNA extraction and molecular techniques; patch-clamp is a plus.
• Maintaining accurate records and contributing to data collection and reports.

Responsibilities

• Provide day-to-day technical support to the PI and lab team.
• Maintain and differentiate iPSC cultures and derive neuronal cell types.
• Perform immunocytochemistry, fluorescence microscopy, RNA extraction and molecular biology tasks.
• Assist with RNA-seq sample prep and data handling; ensure quality control.
• Keep accurate lab records and contribute to presentations and publications.
• Collaborate across the team, maintain equipment and ensure safety compliance.

Education

MSc in Neuroscience or related subject

Honours degree in Neuroscience or related subject

Induced pluripotent stem cell (iPSC) models

Collaborative team experience

Maintaining iPSC cultures and deriving iPSC neurons

Tools

Immunocytochemistry (ICC)

Fluorescence microscopy

RNA extraction

Molecular biology techniques

Patch-clamp electrophysiology

Job description

The University of Sheffield seeks a Research Technician to support SITraN’s Friedreich’s ataxia project. You will maintain iPSC cultures, generate iPSC-derived neurons, and support cellular/molecular studies including ICC, fluorescence microscopy and RNA-seq sample prep.

The role involves data collection, record-keeping and teamwork across a multidisciplinary neuroscience lab, with opportunities to develop technical expertise.