iPSC Neuron FA Research Associate

Dunhillmedical; Sheffield; On-site; GBP 39,000 - 47,000; Full time

Benefits offered by this job

Hybrid working opportunities

Generous pension scheme

Flexible benefits and leave

Job summary

The University of Sheffield is seeking a Research Associate to model Friedreich’s ataxia using human iPSC-derived neurons. Working within SITraN, you will develop, execute and interpret experiments to understand disease mechanisms and responses to therapies.

You will collaborate across disciplines and contribute to publications and funding applications. The role emphasizes iPSC culture, neuronal differentiation, and integration of multidisciplinary data, with opportunities to mentor students and

Qualifications

• PhD in Neuroscience or related subject.
• Demonstrable experience using induced pluripotent stem cell (iPSC) models.
• Experience of working collaboratively in research teams.
• Ability to plan, conduct and interpret experimental research.

Responsibilities

• Plan and conduct experimental research on FA using iPSC-derived neurons.
• Differentiate iPSCs into neuronal cell types and maintain cultures.
• Develop protocols and troubleshoot technical challenges.
• Integrate cellular, electrophysiological and molecular data to address hypotheses.
• Maintain accurate experimental records and deliver milestones.
• Prepare findings for presentations, meetings and manuscripts.
• Support grant applications and future research directions.
• Mentor students and junior staff as needed.

Skills

iPSC models leadership

Neuroscience research

Collaborative teamwork

Data interpretation

Education

PhD in Neuroscience or related subject

Tools

Immunocytochemistry

RNA sequencing

Patch-clamp electrophysiology

Job description

The University of Sheffield is seeking a Research Associate to model Friedreich’s ataxia using human iPSC-derived neurons. Working within SITraN, you will develop, execute and interpret experiments to understand disease mechanisms and responses to therapies.

You will collaborate across disciplines and contribute to publications and funding applications. The role emphasizes iPSC culture, neuronal differentiation, and integration of multidisciplinary data, with opportunities to mentor students and