Higher or Senior Scientific Officer

TN United Kingdom; London; On-site; GBP 40,000 - 60,000; Full time

Job summary

A leading research institute is seeking a Higher or Senior Scientific Officer to lead innovative research in molecular genomics and single cell sequencing related to cancer evolution. This role offers a dynamic research environment with access to state-of-the-art facilities and collaboration opportunities with top researchers in the field. The successful candidate will have a PhD in molecular biology and expertise in advanced NGS technologies, contributing to impactful cancer research.

Benefits

Dynamic and supportive research environment

Access to state-of-the-art facilities

Professional development opportunities

Collaboration with leading researchers

Competitive salary and pension

Qualifications

• PhD in molecular biology or relevant area required.
• Proven expertise in advanced NGS technologies.
• Hands-on experience with single-cell technologies.

Responsibilities

• Lead molecular genomics and single cell sequencing studies.
• Undertake research into colorectal cancer development.
• Generate molecular genomics data from various sample types.

Skills

Advanced NGS experiments

Single cell technologies

Good communication skills

Education

PhD in molecular biology or relevant area

Undergraduate degree in biological or quantitative subject

Job description

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Higher or Senior Scientific Officer, Sutton

Client: The Institute of Cancer Research

Location: Sutton, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Reference:

35e587dd2069

Job Views:

3

Posted:

23.05.2025

Expiry Date:

07.07.2025

Job Description:

Under the guidance of Prof Trevor Graham, we are seeking to recruit a Higher or Senior Scientific Officer to lead molecular genomics and single cell sequencing studies of cancer evolution. The principal duty of the post will be to undertake research into the evolutionary dynamics that underpin colorectal cancer development and response to treatment. The post holder will lead experimental wet-lab work to generate molecular genomics data, particularly single cell data, from patient material, cell lines, organoids, and other sample types.

About you

The successful candidate must have:

• PhD in molecular biology or other relevant area. Undergraduate degree in biological or quantitative subject.
• Ability to perform advanced NGS experiments for the analysis of cancer genomes.
• Ability to conduct single cell/nuclei dissociation, sorting, and NGS analysis in cell lines and/or patient biopsies.
• Proven expertise in advanced NGS technologies, including RNA-seq, DNA-seq, and single-cell sequencing.
• Hands-on experience with single-cell technologies such as scRNA-seq, scATAC-seq, or spatial transcriptomics.
• Good communication skills and the ability to interact effectively with other team members.

Department/Directorate Information

The Centre for Evolution and Cancer (CEC), within the Division of Cancer Biology, is a multidisciplinary centre, comprising around 50 staff dedicated to understanding cancer evolution and leveraging this knowledge for translational benefit. Our interests span early detection through to treatment of metastatic disease. The CEC brings together expertise in evolutionary theory, computational biology, and bioinformatics, along with cutting-edge research ability in cell and molecular biology, to provide a stimulating and creative interdisciplinary environment where new approaches to tackling cancer can thrive.

The Genomics and Evolutionary Dynamics team combines molecular and cellular biology with mathematical and computational modelling to study the evolution of malignancy. We focus on early detection in the gastrointestinal tract, colorectal cancer evolution and treatment response, and pan-cancer genomics. We perform basic research into the biology of the human body in health and disease and translate our findings to improve clinical care of patients affected by cancer.

What we offer

• A dynamic and supportive research environment
• Access to state-of-the-art facilities and professional development opportunities
• Collaboration with leading researchers in the field
• Competitive salary and pension