Global Commercial Director - Immunology

AstraZeneca plc; Cambridge; On-site; GBP 150,000 - 230,000; Full time

Job summary

AstraZeneca plc in Cambridge, UK is seeking a Global Commercial Director for Immunology to shape and drive the global commercial strategy for SLE and potential indications. You will collaborate with Medical Affairs, Pricing, Market Access, and R&D to translate strategy into market-ready plans.

The role requires extensive immunology commercial experience, strong strategic judgment, and the ability to lead through influence in a complex matrix. Competitive benefits and career growth are offered.

Responsibilities

• Develop and implement global commercial strategy for SLE and lifecycle-management opportunities.
• Lead cross-functional initiatives with Medical Affairs, Pricing and Market Access, Market Development, and Regulatory to ensure alignment.
• Collaborate with regional and country teams to gather market insights and translate them into global guidance and resources.
• Oversee launch-readiness activities for potential indications and optimize resource allocation across markets.
• Drive performance reviews with dashboards and actionable business insights.

Job description

Role: Global Commercial Director - Immunology

Location: Cambridge UK

Salary: Competitive + Excellent Benefits

About AstraZeneca

At AstraZeneca, we are driven by a bold ambition: to deliver life-changing medicines that help achieve clinical remission in immune-mediated diseases. We have already made significant progress through the launch of a leading biologic treatment for systemic lupus erythematosus (SLE) , the recent launch of a subcutaneous formulation has expanded this further.

With four further Phase 3 development programs currently ongoing in Cutaneous Lupus (CLE), Systemic Sclerosis (SSc), Lupus Nephritis (LN) and Myositis (IIM), we are now excited to expand and reach additional specialties & patient groups. This is an opportunity to contribute to the continued evolution of an important Immunology franchise and help deliver both near-term brand performance and long-term value.

About the role

As Global Commercial Director , you will contribute to the development and implementation of global commercial strategy across its in-market SLE indication and mid-term lifecycle-management opportunities.

You will support lifecycle launch readiness for potential new indications while also helping to evolve and optimize resources for the existing SLE business. This will require using your existing immunology commercial experience and understanding and applying it to strong strategic thinking, sound commercial judgement.

Given how many of these areas are new to AZ it will also require the ability to bring together multiple inputs from across the organization to anticipate future needs and develop practical approaches in line with the experience you have gained through previously commercializing similar indications in rheumatology/dermatology.

Working across a global matrix, you will partner closely with regional and country commercial teams and colleagues in Medical Affairs, Pricing and Market Access, Market Development, Advocacy, Insights and Analytics, R&D, Regulatory, and other relevant functions. You will lead through influence, build alignment across diverse stakeholders, and translate strategy into market ready plans and deliverables.

Key responsibilities

Driving growth and lifecycle management

• Contribute to the development and evolution of the global commercial strategy across the in-market SLE indication and mid-term lifecycle-management opportunities.


• Translate strategic priorities into clear plans, recommendations, milestones, and deliverables for defined brand and lifecycle-management workstreams.


• Bring together clinical, customer, market, competitive, access, and business inputs to identify implications, anticipate future needs, and inform strategic choices.


• Lead workstreams or contribute to global launch-readiness activities for potential mid-term lifecycle-management indications, including planning, cross-functional alignment, milestone tracking, and issue resolution.


• Partner with regional and country teams to gather market feedback, support implementation, and identify opportunities to improve global guidance and resources.

Cross-functional and matrix effectiveness

• Build effective partnerships across Commercial, Medical Affairs, Pricing and Market Access, Market Development, Advocacy, Insights and Analytics, R&D, Regulatory, and other relevant functions.


• Navigate a complex global matrix and influence stakeholders across functions, geographies, and levels without direct authority.


• Contribute to global team meetings, governance forums, and cross-functional working groups, ensuring actions and decisions are followed through.

Insights and external engagement

• Partner with Insights and Analytics colleagues to develop and apply a robust understanding of market dynamics, patient and customer needs, behaviours, barriers, and opportunities to inform strategic planning, launch readiness and resource development.


• Support engagement with external scientific experts, healthcare professionals, patient advocacy organizations, and other relevant stakeholders, in accordance with applicable policies and standards.

Project and budget management

• Lead complex, multi-stakeholder projects from planning through delivery, managing scope, milestones, dependencies, risks, and outcomes.


• Coordinate project teams and agency partners as appropriate to deliver high-quality outputs while manage allocated budgets responsibly, prioritizing resources to deliver maximum impact and ensuring appropriate tracking, forecasting, and reporting.


• Contribute to performance reviews through appropriate measures, dashboards, progress updates, and business insights.

Essential qualifications and experience

• Experience in launch and in-market commercialisation of advanced treatments such as biologics in SLE or other relevant immunology indications in rheumatology or dermatology is essential for this role.


• Experience in a significant country commercial role, with an understanding of how global strateg