Global Development Medical Director, Late Respiratory and Immunology Clinical Development

AstraZeneca; Cambridge; Hybrid; GBP 120,000 - 150,000; Full time

Job summary

AstraZeneca is seeking a Global Development Medical Director to provide medical and scientific leadership for respiratory and immunology programs from mid to late-stage development. You will drive study design, interpretation, and regulatory interactions while building a global expert network.

You will collaborate across safety, regulatory, and operations, mentoring teams and contributing to clinical publications. Flexibility and international teamwork are central to this role.

Qualifications

• MD or MD/PhD degree required.
• 3+ years of pharmaceutical industry experience and 3+ years of clinical research experience.
• Demonstrated partnership and cross-country collaboration skills.
• Fluent in English with strong presentation and communication skills.
• Ideal background in pulmonary medicine, immunology, rheumatology, allergy, or dermatology.

Responsibilities

• Provide medical and scientific leadership in global development of respiratory and immunology medicines.
• Lead the design, execution and interpretation of late-stage clinical trials.
• Build relationships with external scientific experts.
• Collaborate with Patient Safety, Regulatory Affairs, and Clinical Operations.
• Lead medical monitoring of trials (Ph2b and later) and support Early programs.
• Provide expert input for regulatory documents and interactions with authorities.
• Develop and review protocols, informed consent, investigator’s brochure and other clinical documents.
• Contribute to scientific publications and presentations at meetings and congresses.

Skills

Fluent English

Cross-country collaboration

Medical leadership

Education

MD or MD/PhD degree

Job description

As a Global Development Medical Director, you will support the clinical project team and assist the Global Clinical Project Leader and Global Clinical Head with the design & interpretation process, establishing clear design objectives for clinical programs and studies. You will provide medical input into the content of core labelling texts and medical support for commercial activities, support for medical monitoring of clinical studies. And, you will also provide medical and scientific expertise as well as tactical and strategic medical input to the development of AstraZeneca’s compounds; primarily from Phase IIb to Phase IV. This includes the design, delivery and interpretation of pivotal clinical trials and of studies that further characterize the overall benefit and risk and value of Respiratory and Immunology products in late-stage development.

In the BioPharmaceuticals Research & Development, Late-stage Development, Respiratory & Immunology function you will work in a truly international working environment, with opportunities to meet and discuss with key external experts, other medical colleagues and experts in basic science, as well as commercial and regulatory functions.

Our therapy area aligned groups of physicians and scientists provide clinical guidance and scientific leadership for clinical development programs within AstraZeneca's global organization.

The Global Development Medical Director will work in a wide range of aspects in pharmaceutical medicine, and due to the global responsibilities, there will be a multitude of contacts with health authorities, colleagues and marketing companies within AstraZeneca. This is an opportunity to take on the challenges of clinical development in a group of positive, focused and highly motivated colleagues.

What You Will Do

• Be involved in providing medical and scientific leadership in the global development of new medicines targeted at indications in the field of respiratory diseases and wider range of immunological disorders
• Have an important role providing medical and scientific leadership in the innovative design, execution and interpretation of clinical trials in one or more development programs.
• Build strong relationships with a network of external scientific experts.
• Work closely with colleagues in other functions including Patient Safety, Regulatory Affairs, and Clinical Operations.
• Be involved primarily in late stage (Ph2b and later) clinical programs while also collaborating with clinical colleagues supporting Early (R\&I) stage programs and medical affairs.
• Lead and contribute to medical monitoring of trials
• Provide expert medical input into the preparation of regulatory documents and interactions with regulatory authorities.
• Provide expert medical and scientific analysis and interpretation of data from ongoing studies and in the literature.
• Develop and review protocols, informed consent, investigator’s brochure and other clinical development documents.
• Participate in the preparation of scientific publications and presentations at scientific meetings and congresses.

For This Role, You Will Need

• MD or MD/PhD Degree
• 3+ years of pharmaceutical industry experience, 3+ years of clinical research experience in the academic or clinical practice setting
• Demonstrated partnership and collaboration skills, including acting as the leader and clearly communicating across countries and cultures
• Fluent in oral and written English, with good presentation skills and effective communication
• Ideal candidate has a background in: Pulmonary medicine, Immunology, Rheumatology, Allergy, or Dermatology .

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.

Join us in our unique and bold world.

Date Posted 22-Sep-2026

Closing Date Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.