Enterprise IT Architecture Leader & Strategy

Genome Research Limited (GRL); United Kingdom; Hybrid; GBP 86,000 - 98,000; Full time

Benefits offered by this job

Wellbeing program

Flexible working policy

Inclusive culture

Career development support

Job summary

Genome Research Limited (GRL) seeks a Head of Enterprise IT Architecture to lead architecture strategy, governance, and standards across the Wellcome Sanger Institute’s IDS function. You will chair the Design Authority and coordinate architecture across enterprise applications, web, data, compute, and infrastructure.

You will partner with senior leaders to ensure designs meet security, scalability, and sustainability goals while guiding technology roadmaps and reducing technical debt in a

Qualifications

• Knowledge of TOGAF or other enterprise architecture frameworks.
• In‑depth knowledge of cloud, data, integration, and application architecture.
• Architecture principles, standards development, and technology road mapping.
• IT risk management, technical debt management and obsolescence planning.
• Demonstrable leadership in IT solution architecture.
• Experience in leading design governance (e.g., Technical Design Authority).
• Proven experience reducing technical debt in complex IT estates.
• Experience managing multi-disciplinary architectural teams.
• Ability to translate institutional strategy into actionable architecture roadmaps.
• Ability to evaluate and select IT platforms, infrastructure, and tools.
• Strong understanding of data interoperability and standardisation practices.
• Excellent stakeholder communication and influencing skills.

Responsibilities

• Provide strategic leadership for architecture across a complex technology environment.
• Lead and coordinate technical leads across enterprise applications, web, scientific compute, databases and infrastructure.
• Chair the Design Authority and oversee architectural governance.
• Develop and maintain architecture principles, standards, and roadmaps.
• Review and approve key solution designs ensuring alignment with standards and goals.
• Collaborate with senior leaders to align IT architecture with stakeholder requirements.
• Guide adoption of new technologies with focus on security, scalability, and sustainability.
• Manage technical risk and reduce debt while promoting interoperability.

Skills

TOGAF knowledge

Cloud architecture

Data integration

Architecture governance

IT risk management

Technical debt reduction

Leadership in architecture

Multi-disciplinary teams

Strategic roadmaps

Platform evaluation

Data interoperability

Stakeholder communication

Cross-team collaboration

Technical diplomacy

Job description

Genome Research Limited (GRL) seeks a Head of Enterprise IT Architecture to lead architecture strategy, governance, and standards across the Wellcome Sanger Institute’s IDS function. You will chair the Design Authority and coordinate architecture across enterprise applications, web, data, compute, and infrastructure.

You will partner with senior leaders to ensure designs meet security, scalability, and sustainability goals while guiding technology roadmaps and reducing technical debt in a