Antibody Discovery and Engineering Scientist

TN United Kingdom; Slough; On-site; GBP 40,000 - 60,000; Full time

Job summary

A leading company in antibody drug discovery is seeking an Antibody Discovery and Engineering Scientist in Slough. This role involves developing innovative antibody design techniques and requires a PhD in molecular biology. Candidates should have experience in antibody discovery and strong analytical skills.

Qualifications

• Experience with in vitro display libraries for discovery and engineering.
• Motivated, detail-oriented, with strong communication skills.
• Ability to meet deadlines.

Responsibilities

• Develop and validate antibody design approaches.
• Collaborate with computational scientists on AI/Deep learning.
• Present data at meetings.

Skills

Data analysis

Communication

Molecular visualisation

NGS data analysis

Education

PhD or equivalent in molecular biology and protein biochemistry

Tools

Flow cytometry

Surface plasmon resonance

Bio-layer interferometry

Job description

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Antibody Discovery and Engineering Scientist, Slough

Client: Next-Link

Location: Slough, United Kingdom

Job Category: Other

EU work permit required: Yes

Job Reference: 6731d63b8e44

Job Views: 3

Posted: 23.05.2025

Expiry Date: 07.07.2025

Job Description:

Role overview
Our client is a world leader in antibody drug discovery and development. This is a unique opportunity to join the Antibody Discovery team working with cutting-edge technologies to help shape the delivery of next-generation antibody therapeutics.

This role involves developing and validating new sequence-based and structure-based antibody design approaches, including hit identification, sequence optimisation, and in silico de novo antibody design. It is laboratory-based and requires detailed knowledge of molecular biology and microbiological methods, with a proven track record in antibody discovery or protein engineering.

**Responsibilities:**
• Play a key role in discovering therapeutic monoclonal antibodies to support the pipeline and create value for patients.
• Use yeast display for antibody discovery and optimisation.
• Design and perform selections with synthetic display libraries for in silico de novo antibody discovery.
• Prepare and analyse NGS libraries to support discovery and engineering.
• Collaborate with computational scientists to develop AI/Deep learning and structure-based approaches.
• Contribute to new methodologies in antibody display and engineering.
• Work across project teams to meet timelines.
• Present data at meetings.

Requirements:

Profile:
• PhD or equivalent in molecular biology and protein biochemistry, ideally in the antibody field.
• Experience with in vitro display libraries for discovery and engineering.
• Experience with biochemical techniques like flow cytometry, surface plasmon resonance, or Bio-layer interferometry.
• Skills in computational platforms, molecular visualisation, and NGS data analysis.
• Motivated, detail-oriented, with strong data analysis and communication skills.
• Ability to meet deadlines.