Antibody Discovery and Engineering Scientist

ZipRecruiter; Slough; On-site; GBP 35,000 - 55,000; Full time

Job summary

A leading biotechnology firm based in Slough is seeking skilled scientists to join their Antibody Discovery team. This full-time role involves developing novel antibody therapeutics for serious diseases and requires a PhD in relevant scientific fields. Candidates will work on innovative methodologies, applying both in vitro and computational approaches in a dynamic and collaborative environment.

Qualifications

• PhD with molecular biology and protein biochemistry knowledge, ideally in antibodies.
• Experience with in vitro display libraries is essential.
• Strong analytical skills and the ability to meet deadlines.

Responsibilities

• Discover therapeutic monoclonal antibodies for patients.
• Utilize yeast display technology for antibody discovery.
• Collaborate with computational scientists for AI/deep learning applications.

Skills

Molecular biology

Protein biochemistry

Computational skills

Data analysis

Attention to detail

Communication

Education

PhD or equivalent

Tools

Flow-cytometry

SPR

BLI

Molecular visualization software

NGS data analysis tools

Job description

Job Description

Overview

The role will be based full time onsite in slough for a 12 month initial contract, starting in June and is an ideal role for scientists who are looking to start working in industry.

Join world leaders in antibody drug discovery and development. This unique opportunity allows you to work with a cutting-edge Antibody Discovery team, helping shape the delivery of next antibody therapeutics.

You'll be part of a dynamic team of scientists developing and validating new sequence-based and structure-based antibody design approaches, including antibody hit identification, sequence optimization, and in silico de novo antibody design. This laboratory-based role requires molecular biology and microbiological expertise, with antibody discovery or protein engineering experience being highly advantageous.

Responsibilities

• Discover therapeutic monoclonal antibodies for patients suffering with serious disease
• Utilize yeast display technology for human antibody discovery and optimization
• Design and perform selections using synthetic display libraries to support antibody discovery projects
• Prepare and analyze next sequencing (NGS) libraries
• Collaborate with computational scientists to apply AI/Deep learning and structure-based approaches
• Develop new methodologies in antibody display and engineering
• Deliver results against timelines across project teams
• Present experimental data at cross-functional meetings

Requirements

• PhD (or equivalent) with molecular biology and protein biochemistry knowledge, ideally in antibodies
• Experience with in vitro display libraries for discovery, affinity maturation, or protein engineering
• Knowledge of biochemical characterization techniques (flow-cytometry, SPR, BLI)
• Computational skills including molecular visualization and NGS data analysis
• Strong attention to detail and critical data analysis abilities
• Proven ability to meet deadlines
• Excellent communication skills