Postdoctoral Researcher– Therapeutic Resistance in Brain Cancer

TN United Kingdom; Oxford; On-site; GBP 30,000 - 45,000; Full time

Job summary

A leading research institution is seeking a motivated Postdoctoral Researcher to explore therapeutic resistance in brain cancer. This role involves cutting-edge research using advanced techniques to uncover vulnerabilities in glioblastoma, contributing to impactful cancer treatment strategies. Ideal candidates will have a PhD in a relevant field and a strong publication record.

Qualifications

• Strong track record of research excellence with first-author publications.
• Ability to manage complex projects and analyze large datasets.
• Excellent communication skills for interdisciplinary collaboration.

Responsibilities

• Manage own academic research and collaborate with computational and clinical researchers.
• Investigate mechanisms of therapeutic resistance in glioblastoma.
• Contribute to the scientific development of the lab.

Skills

Molecular biology techniques

Advanced microscopy

Quantitative image analysis

Primary tissue culture

Education

PhD in cancer biology, molecular biology, medicine, or neuroscience

Job description

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Postdoctoral Researcher– Therapeutic Resistance in Brain Cancer, Oxford

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Client:

University of Oxford

Location:

Oxford, United Kingdom

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

fdbddbcb673d

Job Views:

3

Posted:

21.05.2025

Expiry Date:

05.07.2025

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Job Description:

We are seeking

a highly motivated and ambitious Postdoctoral Researcher to join our team in addressing a key question in cancer biology: why brain cancer cells resist current therapies. This role offers a unique opportunity to investigate the mechanisms of therapeutic resistance in glioblastoma and contribute to the development of more effective treatment strategies.

Our research focuses on understanding how tumour cell plasticity and dynamic cell state transitions drive resistance, and aims to identify actionable vulnerabilities that could inform future therapies. You will work with cutting-edge models and technologies—including patient-derived glioblastoma organoids, CRISPR-based screens, mass cytometry, and advanced microscopy—to dissect these complex biological processes.

You will be responsible for managing your own academic research, collaborating with computational and clinical researchers, and contributing to the scientific development of the lab. This is an exciting opportunity for a researcher passionate about translational cancer research and making a meaningful impact in the field.

About you

You will hold a PhD (or be close to completion) in a relevant field such as cancer biology, molecular biology, medicine, or neuroscience. Your expertise will include molecular biology techniques, advanced microscopy, quantitative image analysis, and primary tissue culture, all of which will support your contributions to high-quality, translational cancer research.

You will have a strong track record of research excellence, including first-author publications in peer-reviewed journals, and demonstrate the ability to manage complex projects, analyse large datasets, and deliver results to tight deadlines. Your collaborative mindset and excellent communication skills will enable you to work effectively within an interdisciplinary team and present your findings confidently to both academic and clinical audiences.