Postdoctoral Researcher - Therapeutic Resistance in Brain Cancer

UAG; Oxford; On-site; GBP 38,000 - 47,000; Full time

Job summary

A leading research institution is seeking a motivated Postdoctoral Researcher to explore therapeutic resistance in glioblastoma. This role involves cutting-edge research using advanced techniques and collaboration with interdisciplinary teams. Ideal candidates will hold a PhD in a relevant field and have a strong publication record, alongside excellent communication skills.

Benefits

Excellent contributory pension scheme

38 days annual leave

Comprehensive childcare services

Family leave schemes

Cycle loan scheme

Discounted bus travel

Membership to social and sports clubs

Qualifications

• PhD (or close to completion) in a relevant field.
• Strong track record of research excellence, including first-author publications.
• Experience with interdisciplinary approaches and bioinformatics is advantageous.

Responsibilities

• Manage academic research and collaborate with computational and clinical researchers.
• Investigate mechanisms of therapeutic resistance in glioblastoma.
• Contribute to the scientific development of the lab.

Skills

Molecular biology techniques

Advanced microscopy

Quantitative image analysis

Primary tissue culture

Data analysis

Collaboration

Communication skills

Education

PhD in cancer biology, molecular biology, medicine, or neuroscience

Job description

About the role

We are seeking a highly motivated and ambitious Postdoctoral Researcher to join our team in addressing a key question in cancer biology: why brain cancer cells resist current therapies. This role offers a unique opportunity to investigate the mechanisms of therapeutic resistance in glioblastoma and contribute to the development of more effective treatment strategies.

Our research focuses on understanding how tumour cell plasticity and dynamic cell state transitions drive resistance, and aims to identify actionable vulnerabilities that could inform future therapies.

You will work with cutting-edge models and technologies—including patient-derived glioblastoma organoids, CRISPR-based screens, mass cytometry, and advanced microscopy—to dissect these complex biological processes.

You will be responsible for managing your own academic research, collaborating with computational and clinical researchers, and contributing to the scientific development of the lab. This is an exciting opportunity for a researcher passionate about translational cancer research and making a meaningful impact in the field.

About you

You will hold a PhD (or be close to completion) in a relevant field such as cancer biology, molecular biology, medicine, or neuroscience. Your expertise will include molecular biology techniques, advanced microscopy, quantitative image analysis, and primary tissue culture, all of which will support your contributions to high-quality, translational cancer research.

You will have a strong track record of research excellence, including first-author publications in peer-reviewed journals, and demonstrate the ability to manage complex projects, analyse large datasets, and deliver results to tight deadlines. Your collaborative mindset and excellent communication skills will enable you to work effectively within an interdisciplinary team and present your findings confidently to both academic and clinical audiences.

Experience or interest in applying interdisciplinary approaches and additional expertise in areas such as FACS/mass cytometry, bioinformatics, or in vivo work (holding a personal licence) would be advantageous.

Application Process

If you would like to discuss this role, please contact Dr Lucy Brooks [e-mail]. You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae, and the names and contact details of two referees as part of your online application.

The closing date for applications isnoononMonday, 16th June 2025.

What We Offer

As an employer, we genuinely care about our employees' wellbeing and this is reflected in the range of benefits that we offer including:

• An excellent contributory pension scheme

• 38 days annual leave

• A comprehensive range of childcare services

• Family leave schemes

• Cycle loan scheme

• Discounted bus travel and Season Ticket travel loans

• Membership to a variety of social and sports clubs

Committed to equality and valuing diversity

£38,674 to £46,913 per annum