Scientist (High Throughput Screening, Antibody Discovery)

ZipRecruiter; England; On-site; GBP 33,000 - 39,000; Full time

Job summary

A leading organization in cancer research is seeking a Scientist for High Throughput Screening in Antibody Discovery. The role involves developing and executing assays to identify therapeutic antibodies. Candidates should possess a PhD and experience in biochemical technologies. The position offers a flexible working environment and a competitive salary, alongside a generous benefits package aimed at fostering innovation and collaboration.

Benefits

Up to 12% pension contribution

Income protection

Career development

Healthy work-life balance

Qualifications

• Experience developing assays for drug candidates, especially antibodies.
• Strong knowledge of HTS technologies in antibody discovery.

Responsibilities

• Develop and execute high throughput screening assays for antibodies.
• Contribute to project progress within a multidisciplinary team.
• Record, track, and present data in team meetings.

Skills

Biochemical Technologies

Cell-Based Assays

High Throughput Screening

Collaboration

Communication

Education

PhD or equivalent experience

Tools

Flow Cytometry

High Content Imaging

ELISA

MSD

HTRF

Laboratory Automation

Job description

Job Description

200 staff. Limitless Potential. One team - Cancer Research Horizons.

Scientist - High Throughput Screening (Antibody Discovery) - Under the leadership of Nick Tribble

Salary: £33,000 - £38,150 per annum depending on experience, plus benefits (includes up to 12% pension contribution and income protection)

Reports to: Principal Scientist, Antibody Discovery

Department: Research and Innovation

Contract: Permanent

Hours: Full time 35 hours per week (flexible working requests considered)

Location: Cori Building, Granta Park, Cambridge

Closing date: 26th May 2025 23:55. This vacancy may close earlier if a high volume of applications is received or once a suitable candidate is found. We recommend applying early. For reasonable adjustments, please contact us.

Visa Sponsorship: Cancer Research UK can consider visa sponsorship (conditions apply). Please indicate this on your application if applicable.

Interview schedule: Initial screening via MS Teams in the week commencing 2nd June 2025; in-person interviews at Granta Park on 11th-12th June 2025.

At Cancer Research UK, we exist to beat cancer.

We have an exciting opportunity within our Drug Discovery team for an experienced Scientist to enhance our capabilities in therapeutic antibody discovery.

About CRUK Drug Discovery

As the world's largest medical research charity, we've helped bring eleven new cancer drugs to market. We aim to bring more effective treatments to patients faster through our new Cancer Research Horizons (CRH), which consolidates our drug discovery efforts and leverages our academic and technological networks to innovate in cancer treatment.

Based in Cambridge, Glasgow, London, and Newcastle, CRH employs ~200 staff from diverse backgrounds. In this lab-based role, you will use biochemical and cell-based high throughput screening technologies to develop and execute assays within the Antibody Discovery team. Experience with developing assays to identify early-stage drug candidates, especially antibodies, is essential.

We offer an inclusive environment that fosters creativity, technological innovation, and scientific excellence, encouraging our colleagues to attend conferences, present posters, and publish papers.

What will I be doing?

• Developing and executing high throughput screening assays for therapeutic antibody identification and characterization.
• Contributing to project progress within a multidisciplinary team.
• Using biochemical and cell-based assays to determine functional properties of antibodies (e.g., IC50, EC50).
• Working with various assay formats, detection technologies, and automation to maximize efficiency.
• Maintaining technical expertise in assays development and antibody discovery.
• Recording, tracking, and presenting data in team meetings.

What skills will I need?

• PhD or equivalent experience in a relevant field.
• Strong knowledge of biochemical and cell-based HTS technologies used in pre-clinical antibody discovery.
• Experience developing and running high throughput cell-based assays, preferably for antibodies.
• Proficiency with assay formats and detection technologies such as flow cytometry, high content imaging, ELISA, MSD, and HTRF.
• Experience with laboratory automation solutions (e.g., Viaflo, Hamilton, HighRes) is highly desirable.
• Proactive attitude, ability to prioritize, multitask, and adapt.
• Strong collaborative and communication skills.
• Interest in scientific innovation and capability development.

What will I gain?

Our values—Bold, Credible, Human, Together—guide us. We seek individuals who embody these values to help us beat cancer.

We support your wellbeing with a generous benefits package, career development, and a healthy work-life balance. Explore our benefits on our careers webpage.

How do I apply?

We use anonymized shortlisting to promote equality. CVs are required but not reviewed until interview invitation. Complete the work history section of the application form for fair assessment. For more information, visit our website or contact us. Follow us on LinkedIn, Facebook, Instagram, X, and YouTube for updates.