Director of Medical Affairs & HTA Statistics

Cytel; Greater London; On-site; GBP 90,000 - 120,000; Full time

Job summary

Cytel Inc. is seeking a Medical Affairs & HTA Statistician to provide strategic statistical leadership across the product lifecycle, with emphasis on real-world evidence, comparative effectiveness, and Health Technology Assessment.

You will translate clinical, observational, and real-world data into scientifically robust evidence addressing questions relevant to patients, clinicians, payers, and healthcare systems.

Qualifications

• Senior-level statistical/biostatistical experience within the pharmaceutical or healthcare environment.
• Demonstrated experience delivering Medical Affairs and/or HTA statistical work packages.
• Broad methodological expertise spanning clinical, observational, and real-world data.

Responsibilities

• Provide statistical leadership for Medical Affairs and HTA evidence-generation activities.
• Support development of evidence strategies addressing clinical, patient, payer, and healthcare-system questions.
• Design and analyse observational and real-world evidence studies.
• Apply epidemiological and statistical methodologies to real-world and clinical data.
• Conduct comparative-effectiveness assessments and indirect treatment comparisons.
• Support synthetic-control approaches, Phase IV studies, and other post-approval evidence-generation activities.
• Apply HTA/HEOR methodologies and contribute statistical expertise to evidence packages supporting access and reimbursement decisions.
• Assess data relevance and quality, quantify and communicate uncertainty, and strengthen methodological credibility of HTA submissions and scientific discussions.
• Interpret clinical and observational evidence and translate analyses into clear scientific conclusions.
• Support publications, congress activities, and other scientific communications where required.
• Apply modern analytical methods, including machine learning, where scientifically appropriate.
• Collaborate with Development Statistics, Epidemiology, Real-World Evidence teams, Medical functions, and external partners.
• Communicate statistical concepts and findings effectively to cross-functional and external stakeholders.

Job description

Cytel Inc. is seeking a Medical Affairs & HTA Statistician to provide strategic statistical leadership across the product lifecycle, with emphasis on real-world evidence, comparative effectiveness, and Health Technology Assessment.

You will translate clinical, observational, and real-world data into scientifically robust evidence addressing questions relevant to patients, clinicians, payers, and healthcare systems.