Developmental Growth & Gap Junctions: Tissue Size Control

THE FRANCIS CRICK INSTITUTE LIMITED; Greater London; Presencial; GBP 21.000 - 25.000; Jornada completa

Descripción de la vacante

The Francis Crick Institute Limited is inviting applications for a Crick PhD project focused on developmental control of tissue growth through local cell communication. The project uses Drosophila, mice, and cell culture to dissect how local cues coordinate with systemic signals to set final tissue size.

Ideal candidates hold a biology degree with MSc/MRes and demonstrate strengths in quantitative biology, computational analysis, and image processing.

Formación

• Degree in biology with an MSc/MRes in a relevant field.
• Experience using quantitative approaches to analyze biological data.
• Interest in developmental biology and tissue growth.

Responsabilidades

• Study gap junctions’ role in growth control using live-imaging and genetic tools.
• Characterize signals coordinating cell cycle exit and tissue size.
• Apply machine-learning based image analysis to quantify developmental patterns.

Conocimientos

Quantitative biology

Computational analysis

Data interpretation

Literature review

Educación

MRes/MSc in a biological discipline

Herramientas

Confocal microscopy

Live-imaging

Optogenetics

Genome engineering

Machine-learning image analysis

Descripción del empleo

The Francis Crick Institute Limited is inviting applications for a Crick PhD project focused on developmental control of tissue growth through local cell communication. The project uses Drosophila, mice, and cell culture to dissect how local cues coordinate with systemic signals to set final tissue size.

Ideal candidates hold a biology degree with MSc/MRes and demonstrate strengths in quantitative biology, computational analysis, and image processing.