Cryo-EM Pathways: Lipid-Enveloped Virus Entry & Assembly

THE FRANCIS CRICK INSTITUTE LIMITED

Greater London

On-site

GBP 21,000 - 26,000

Full time

14 days+

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Job summary

The Francis Crick Institute Limited's Rosenthal Lab invites applications for a Crick PhD project focusing on Cryomicroscopy of lipid-enveloped virus entry and assembly. You will train in single particle cryo-EM, cryo-ET, FIB-milling and subtomogram averaging to image virus processes in cells and in vitro.

Candidates with a background in structural biology, virology or cell biology and hands-on experience in molecular biology or computation are encouraged to apply, with opportunities to study

Qualifications

  • Background in structural biology, virology or cell biology.
  • Experience with experimental methods in molecular biology or virology.
  • Interest in methodological aspects of electron imaging or computation.

Responsibilities

  • Study lipid-enveloped virus entry and assembly using cryo-EM/cryo-ET.
  • Train in single particle cryo-EM, cryo-ET, FIB-milling and subtomogram averaging.
  • Develop imaging and computational image-analysis methods.”

Skills

Structural biology
Virology
Cell biology
Molecular biology
Computation
Electron imaging

Tools

Cryo-EM
Cryo-ET
FIB-milling
Subtomogram averaging

Job description

The Francis Crick Institute Limited's Rosenthal Lab invites applications for a Crick PhD project focusing on Cryomicroscopy of lipid-enveloped virus entry and assembly. You will train in single particle cryo-EM, cryo-ET, FIB-milling and subtomogram averaging to image virus processes in cells and in vitro.

Candidates with a background in structural biology, virology or cell biology and hands-on experience in molecular biology or computation are encouraged to apply, with opportunities to study

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